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Hematology > Quiz 2 > Flashcards

Quiz 2 Flashcards

1
Q

Hematopoletically active marrow in cases of acute blood loss

A

Red marrow

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2
Q

What is the major adult hemoglobin

A

Alpha 2, beta 2

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3
Q

What hormone indirectly inhibits erythropoiesis?

A

Estrogen

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4
Q

Hematopoiesis outside the bone marrow is termed as

A

Extramedullary hematopoiesis

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5
Q

Ribosomal RNA remnants can be visualized in

A

Reticulocyte

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6
Q

Which of the ff is the most mature normoblast?

Basophilic
Pronormoblast
Orthochromic
Polychromatophilic

A

Orthochromic

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7
Q

One gram of hemoglobincan carry a ____ iron

A

3.47 mg

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8
Q

The first stage capable of hemoglobin synthesis

A

Rubricyte

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9
Q

What is the ratio of pyrrole ring to Fe2+ in a single heme molecule?

A

4:1

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10
Q

Protoporphyrin IX ring with Fe2+ at its center is called

A

Heme

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11
Q

What is the first type of cell produced by the developing embryo?

A

Erythrocyte

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12
Q

What is the predominant hemoglobin in fetal development?

A

Alpha 2, gamma 2

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13
Q

In embryonic stage, what are the products being produced

A

HSCs, Primitive erythroblasts, fetal hemoglobins

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14
Q

The affinity of hemoglobin for oxygen is dependent on what factors?

A

Partial pressure of CO2
concentration of 2,3-BPG
pH
Temperature

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15
Q

Nuclear remnants predominantly composed of DNA

A

Howell Jolly bodies

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16
Q

What erythroid precursor can be described as follows: pink cytoplasm
associated with hemoglobin synthesis, condensation of chromation, no
nucleoli pesent

A

Rubricyte

17
Q

Erythropoietin is produced in what organ?

A

Kidney and Liver

18
Q

Dietary iron is absorbed in its ferrous form in what site of the small intestine?

A

duodenum

19
Q

Erythrocyte remains viable for an average of

A

4 months

20
Q

“Dawn of hemoglobinization”

A

Polychromatophilic Normoblast

21
Q

Cluster differentiation marker found in the hematopietic stem cell

A

CD 34

22
Q

Heme synthesis starts and ends in what organelle?

A

Mitochondria

23
Q

Zeta chain globin production is controlled by genes on chromosome

A

16

24
Q

It transports iron from the enterocytes to the circulation

A

Ferroportin

25
Q

considered to be a multi-lineage stimulating factor

A

IL-3

26
Q

It causes mauve lavender color of the blood

A

Sulfhemoglobin

27
Q

In the adult, the usual location for obtaining a bone marrow aspirate is the

A

Iliac crest

28
Q

Polychromatophilic erythrocyte is stained using

A

Wright stain

29
Q

In the third month of gestation, what is the primary site of hematopoiesis?

A

Liver

30
Q

Erythropoiesis in the adult primarily takes place in the

A

Bone marrow

31
Q

What stain and type of staining is used to identify reticulocytes in the blood
smear?

A

Brilliant Cresyl Blue/Supravital Staining

32
Q

Which chemical substances are responsible for differentiation and replication
of the pluripotent stem cell?

A

Cytokines

33
Q

What are the organs of hematopoiesis in fetal life?

A

Spleen and liver

Hematology (28 decks)

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