Quiz 2

Question 1

Hematopoletically active marrow in cases of acute blood loss

Answer 1

Red marrow

Question 2

What is the major adult hemoglobin

Answer 2

Alpha 2, beta 2

Question 3

What hormone indirectly inhibits erythropoiesis?

Answer 3

Estrogen

Question 4

Hematopoiesis outside the bone marrow is termed as

Answer 4

Extramedullary hematopoiesis

Question 5

Ribosomal RNA remnants can be visualized in

Answer 5

Reticulocyte

Question 6

Which of the ff is the most mature normoblast?

Basophilic
Pronormoblast
Orthochromic
Polychromatophilic

Answer 6

Orthochromic

Question 7

One gram of hemoglobincan carry a ____ iron

Answer 7

3.47 mg

Question 8

The first stage capable of hemoglobin synthesis

Answer 8

Rubricyte

Question 9

What is the ratio of pyrrole ring to Fe2+ in a single heme molecule?

Answer 9

4:1

Question 10

Protoporphyrin IX ring with Fe2+ at its center is called

Answer 10

Heme

Question 11

What is the first type of cell produced by the developing embryo?

Answer 11

Erythrocyte

Question 12

What is the predominant hemoglobin in fetal development?

Answer 12

Alpha 2, gamma 2

Question 13

In embryonic stage, what are the products being produced

Answer 13

HSCs, Primitive erythroblasts, fetal hemoglobins

Question 14

The affinity of hemoglobin for oxygen is dependent on what factors?

Answer 14

Partial pressure of CO2
concentration of 2,3-BPG
pH
Temperature

Question 15

Nuclear remnants predominantly composed of DNA

Answer 15

Howell Jolly bodies

Question 16

What erythroid precursor can be described as follows: pink cytoplasm
associated with hemoglobin synthesis, condensation of chromation, no
nucleoli pesent

Answer 16

Rubricyte

Question 17

Erythropoietin is produced in what organ?

Answer 17

Kidney and Liver

Question 18

Dietary iron is absorbed in its ferrous form in what site of the small intestine?

Answer 18

duodenum

Question 19

Erythrocyte remains viable for an average of

Answer 19

4 months

Question 20

“Dawn of hemoglobinization”

Answer 20

Polychromatophilic Normoblast

Question 21

Cluster differentiation marker found in the hematopietic stem cell

Answer 21

CD 34

Question 22

Heme synthesis starts and ends in what organelle?

Answer 22

Mitochondria

Question 23

Zeta chain globin production is controlled by genes on chromosome

Answer 23

16

Question 24

It transports iron from the enterocytes to the circulation

Answer 24

Ferroportin

Question 25

considered to be a multi-lineage stimulating factor

Answer 25

IL-3

Question 26

It causes mauve lavender color of the blood

Answer 26

Sulfhemoglobin

Question 27

In the adult, the usual location for obtaining a bone marrow aspirate is the

Answer 27

Iliac crest

Question 28

Polychromatophilic erythrocyte is stained using

Answer 28

Wright stain

Question 29

In the third month of gestation, what is the primary site of hematopoiesis?

Answer 29

Liver

Question 30

Erythropoiesis in the adult primarily takes place in the

Answer 30

Bone marrow

Question 31

What stain and type of staining is used to identify reticulocytes in the blood smear?

Answer 31

Brilliant Cresyl Blue/Supravital Staining

Question 32

Which chemical substances are responsible for differentiation and replication of the pluripotent stem cell?

Answer 32

Cytokines

Question 33

What are the organs of hematopoiesis in fetal life?

Answer 33

Spleen and liver