Pulmonary vascular disease Flashcards
What is two examples of pulmonary vascular diseases
Pulmonary embolism
Pulmonary hypertension
Define pulmonary embolism
Blood clot traveling from one part of the body to antother part
What is pulmonary embolism medically treated with
anti coagulation
Where does the blood clot lodge in a pulmonary embolism
Peripheral pulmonary artery
Major risk factors of pulmonary embolism
Recent major trauma
Recent surgery
Cancer
Significant cardiopulmonary disease e.g. MI
Pregnancy
Inherited thrombophilia e.g Factor V Leiden
What is thrombophilia
A genetic disorder that means you have a predisposition to blood clots
How can surgery cause blood clotting
In bed after operation, immobility results in clot
Surgery stimulates blood clotting
What are the symptoms of small blood clots to the lungs
Pleuritic chest pain
Cough and haemoptysis
Define pleuritic chest pain
burning or dull pain in the right or the left side of the heart during breathing
Define Isolated acute dyspnoea, and what causes this in a pulmonary embolism
Difficulty in breathing, caused by the blood being ventilated but not perfused
In a massive pulmonary embolism what is the symptom
Cardiac arrest
syncope - loss of consciences
What are the signs of a small pulmonary embolism
Pleural rub - scrunching sound
Pleural effusion - fluid around the lung
Pyrexia - increased temp
What are the signs of a major pulmonary embolism
Tachycardia - increased heart rate
hypotension - low BP
tachypnoea - rapid breathing
hypoxia
How can you test the probability that someone has a pulmonary embolism
Symptoms and signs present
Previous history
Has risk factors
List the different investigations to diagnose pulmonary embolism
Full blood count, biochemistry, blood gases Chest X-Ray ECG D-dimer CT Pulmonary Angiogram (CTPA) V/Q scan Echocardiography Consider CT abdomen and mammography Consider thrombophilia testing
What is the purpose of a D-dimer test?
D-dimer is the product of blood clotting, if D-dimer is negative means unlikely have pulmonary embolism
What does a V/Q scan show
The ventilation and perfusion in the lungs