Pulmonary Flashcards
What is the name of this triad?
1) Asthma
2) Nasal polyps
3) ASA/NSAID allergy
Samter’s Triad
What is Dx GOLD for Asthma and what does it show?
- PFT
- Reversible obstruction: dec. FEV-1, dec. FEV-1 / FVC
MCC of COPD in Cystic Fibrosis
Pseudomonas
TOC for Bronchiectasis
CT scan
What is a polysomnography?
Sleep study
GI symptoms, hyponatremia, patchy unilobar lower lobe infiltrate. Dx?
Legionella Pneumonia
What is the CURB-65 score?
Predict severity of PNA to help determine inpatient vs. outpatient treatment.
What do the following fall under?
- CHF
- Cirrhosis
- Nephrotic Syndrome
- Pulmonary embolism
- Hypoalbuminemia
Transudative
GOLD Dx for active/reactivated TB
Acid-Fast Smear and Sputum Culture (AFB)
4 lab criteria for exudative effusion:
1) Serum Protein >0.5
2) Serum LDH >0.6
3) Pleural fluid LDH > 2/3 normal upper limit for serum LDH.
* *4) GLUCOSE <60
-↓ breath sounds
-Dull percussion
-↓ tactile fremitus
Is found in:
Pleural Effusion
Organism most associated with PNA and bullous myringitis:
Strep pneumoniae
GOLD Dx for Latent/primary TB
PPD
What PNA would be post H. flu infection?
Staph aureus
What gram stain would you find with Strep pneumoniae?
Gram (+) cocci pairs
Cardiac dysrhythmia d/t macrolide use:
QT prolongation
Light’s Criteria
- Serum protein
- Serum pleural fluid lactate dehydrogenase (LDH)
Acute Pancreatitis + Pleural Effusion (seen on CXR). Pleural fluid shows:
Elevated Amylase
Patho of Laryngotracheitis:
Parainfluenza
Sarcoidosis: decrease or increase in ACE?
Increase
TOC for Pulmonary Embolism:
CT pulmonary angiography
In active TB, do we need airborne or droplet precautions?
Airborne
What is the common SE of Rifampin?
Orange discoloration of body fluids.
Tx for Idiopathic Pulmonary Fibrosis
- O2
- Pulmonary rehab
Pt. presents with GI complaints, skin flushing and wheezing. Dx?
Carcinoid Syndrome
What is given to PREVENT risk of Infant Respiratory Distress Syndrome?
Glucocorticoids (MC Betamethasone)
PPD: high-risk, homeless, health-care workers, IVDU, foreign-born
≥ 10 mm
Tx of TB
RIPE
- Rifampin
- Isoniazid (need B6 [Pyridoxine] to prevent peri neuropathy**)
- Pyrazinamide
- Ethambutol
Tx for Psittacosis
Doxy
MCC lung abscess
Aspiration PNA
What is the significance of a high amylase in a pleural fluid?
Signs of:
- Pancreatitis
- Esophageal rupture
- Malignancy
What type of meds are Tiotropium and lpratropium?
Anticholinergics
-↓ breath sounds
-↓ fremitus
-hyperresonance to percussion
Is found in:
Pneumothorax
In a patient with CKD and suspected pulmonary embolism, what diagnostic tool is used?
Ventilation/perfusion scan
How do we Dx Carcinoid Syndrome?
24-hour URINE excretion of 5-hydroxyindoleacetic acid (5-HIAA)
MC presenting symptom of acute pulmonary embolism:
Dyspnea
Rheumatoid Arthritis (RA) + Pneumoconiosis =
Caplan’s syndrome
Elevated LDH and CXR bilateral infiltrates. Dx?
Pneumocystis jirovecii PNA
Carcinoid tumors commonly secrete:
Serotonin
When is Pertussis most contagious?
- Catarrhal stage
- Lasts 1-2 wks
What is Hamman’s sign?
Crunching sound heard during auscultation with Pneumomediastinum.
With low suspicion of pulmonary embolism, what diagnostic tool can we use to R/O?
D-dimer
PPD: immunosuppressed, recent TB contact, abnormal CXR, steroid use
≥ 5 mm
CXR: lobar. What type on PNA is this?
- Pneumococcal (AKA Strep pneumoniae)
- The ONLY lobar PNA!***
Tx for Healthcare Associated Pneumonia (HCAP)
IV Abx and admit (D/T both typical and more resistant organisms)
Long-term complication of obstructive sleep apnea:
Pulmonary HTN
Exposure to shipyard, construction, and insulation occupations may lead to:
Asbestosis
PE findings that aids in differentiating the cause of crackles or rales, heard on lung auscultation:
Egophony
What sleep apnea is associated with Cheyne-Stokes breathing, drug use, or central nervous system disorders?
Central sleep apnea
Dx for Cystic Fibrosis
Elevated sweat chloride test
MCC of Chronic Cor Pulmonale
COPD
What is the name of this triad?
- Stasis (shoulder immobilization)
- Venous injury (recent trauma)
- Hypercoagulability (OCPs)
Virchow triad
Dx for Cor Pulmonale
Right heart cath
Dx GOLD for Pneumomediastinum
CT
Tx of choice for Respiratory Distress Syndrome (Hyaline Membrane Disease)
Surfactant
Newborn baby begins to have difficulties breathing. CXR shows parenchymal infiltrates and fluid in the pulmonary fissures. Dx?
Transient Tachypnea of the Newborn
Bronchitis Tx for cough:
OTC Dextromethorphan or Guaifenesin
MC EKG finding in acute pulmonary embolism:
Sinus tachy
What spirometry values would be seen in COPD?
- ↓ FEV-1
- ↓ FVC
- ↓ FEV1/FVC <70%
Exposure to foundries, sandblasting, mines, stone may lead to:
Silicosis
MCC of Acute Cor Pulmonale
Pulmonary Embolism
MCC of Bronchiectasis
Cystic Fibrosis
MCC of Epiglottitis
H. flu
Tx for Pertussis
Macrolides
Which lung cancer presents with “CCCP” → Central, Cavitary lesions, hyperCa+, Pancoast syndrome?
SCC
In Newborn Chlamydia Pneumonia, what is the cough described as? Does it present with fever?
- Staccato
- NO fever
What is Psittacosis?
Chlamydia psittaci (D/T birds)
When diagnosing PNA in kids, which findings has the highest odds ratio?
Ox sat. <92%
Dx of Pertussis
PCR of nasopharyngeal secretions
What is the name of this triad?
- Hilar adenopathy
- Erythema nodosum
- Polyarthralgia
Lofgren syndrome
Rx for pulmonary arterial hypertension
Sildenafil
How is pertussis spread?
Respiratory droplet
MC opportunistic respiratory infection in patients with AIDS?
Pneumocystis jiroveci
MCC pleural effusion in U.S.
HF
MCC massive pleural effusion (> 1.5–2 L)
Malignancy
Tx for Sarcoidosis
PO Steroids
Tx for lung abscess
- Ampicillin-sulbactam
- Carbapenems
- Clindamycin
Beta 2 Agonists MOA
Increase cAMP (cyclic adenosine monophosphate) to bronchodilate
Tx for Psittacosis in kids and pregnancy
Erythromycin
Screening for lung cancer is tested by ______ and recommended for ______.
Low dose CT ------------------------------------ 55 to 80yo with: -30 pack-year Hx and still smoke OR -Quit within last 15 yrs
Which Dx’s require airborne precautions?
- TB
- Pneumocystis jirovecii
- Measles
- Zoster
Criteria for Pneumocystis PNA and getting Prednisone before Tx with Bactrim
- PaO2 <70 mm Hg
- A-a gradient >35 mm Hg
If unexplained isolated pleural effusion, think _______.
Pulmonary Embolism
Tx for acute asthma exacerbation
Oxygen and beta-2-agonist neb (Albuterol)
MC patho of Bronchiolitis
RSV
Mgmg for pulmonary nodule <6mm and no RFs
No F/U
Albuterol can lead to what electrolyte abnormality?
HypoK
Tx for Infant Respiratory Distress Syndrome
Surfactant
MC and 2nd MC type of lung cancer
Non-small cell:
1st Adenocarcinoma
2nd: SCC
What is the treatment of choice for Pneumococcal (AKA Strep pneumoniae)?
Penicillin
2nd: Azithro or Augmentin
Tx for Pneumothorax
Needle decompression of the chest in 2nd intercostal space at midclavicular line or 5th intercostal space in midaxillary line followed by chest tube insertion
Post-op fever on day 1-2 would likely be:
Atelectasis (partial or complete collapsed lung)
56 yo patient presents with a 6mm pulmonary nodule. What is your next step in management?
If given the options of CT of chest and biopsy, DO BX 1ST
25 yo with has a Hx of DM. She has no TB RFs and is starting a new job at the hospital. What is the minimal number on PPD?
15mm (doesn’t matter that she has DM)
Dx for Sarcoidosis
Bronchoscopy with Bx → noncaseating granulomas
Decreased breath/heart sounds and hyperresonance to percussion is found in:
Emphysema
A 50 yo presents with a community acquired pneumonia. He was previously treated with Azithromycin but he is back reporting no change. What is the next best med?
Levofloxacin (used for bounce-backs)
SE of Ethambutol
Optic neuritis
What is the best treatment for PNA caused by H. flu (HIB, type B MC)?
Ceftriaxone
2nd: Azithro
2nd line Tx for Mycoplasma
Doxy
To identify a bacteria, what is the best initial test?
IFA (indirect fluorescent antibody)
Tx for PNA in HIV pt.
Bactrim
Pt. present with parents. He has a bowel obstruction. What do you worry about?
Cystic Fibrosis
What is the most sensitive and specific pulmonary function test (PFT) for COPD?
Residual Volume (trash that’s left, CO2)
1st and 2nd line Tx for COPD
- Rescue inhaler
- L/A Anticholinergic (Tiotropium) + L/A Beta-2 (Salmeterol)
Pt. presents with lung CA and Hx of endocrine dysfunction. What is the likely lung CA involved?
Small cell (always involves endo)
Pt. with ARDS is placed on Positive end-expiratory pressure (PEEP). What is a side effect?
Pulmonary fibrosis
Pt. presents with an asthma exacerbation. What would you expect to see on ABG?
Respiratory acidosis
≤ 14yo Tx for PNA? What does it switch to at >15yo?
- Amoxi
- Azithro