PSYCHOPHARMACOLOGY - Pharmacokinetics

Question 1

What pharmacokinetic factor of
psychotropic medication is different in
children from adults?

Answer 1

Faster metabolism in children

Question 2

Pharmacokinetic feature of lamotrigine
causing interactions with valproate and
carbamazepine?

Answer 2

hepatic glucuronidation/metabolism

Question 3

What consideration should be taken for an
ultra-rapid metabolizer of CYP2D6 being
prescribed atomoxetine?

Answer 3

Higher dose may be needed

Question 4

Children often require a larger dose

compared to adults due to what weight adjusted characteristic?

Answer 4

Higher GFR

Question 5

Term for proportion of medication taken

that reaches systemic circulation?

Answer 5

Bioavailability

Question 6

Which medication may lead to toxicity in

children due to its zero order kinetics?

Answer 6

Paroxetine

Question 7

Some medications for psychiatric
conditions may seem to lack efficacy in
youth due to which factor in youth?

Answer 7

Relatively immature neural networks