CLINICAL NEUROLOGY - Anti-NMDA-Receptor Encephalitis

Question 1

Child has Anti-NMDA-Receptor
Encephalitis. Pt anxious, confused, waxy flexibility, minimal verbalization and staring episodes. What is initial
treatment for motor symptoms? (2x)

Answer 1

Lorazepam

Question 2

17 yo has flu-like illness, then psychosis, paranoia, catatonia, and LLQ abdomen mass. Test to order? (2x)

Answer 2

Anti-NMDA receptor antibodies

Question 3

16 yo female with memory/confusion issues for three weeks, presents w/ new onset agitation, hallucinations, insomnia, inattention, brief seizure, elevated HR/BP, ovarian lesion on ultrasound, otherwise normal exam. Diagnosis?

Answer 3

Anti-N-methyl-d-aspartate receptor

encephalitis

Question 4

Adolescent admitted for paranoia,
hallucinations, mood lability, then develops facial tics, autonomic instability, obtunded. Adnexal mass on workup. Removal likely to normalize activity of receptor for which neurotransmitter?

Answer 4

Glutamate