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Finals passmed > psychiatry > Flashcards

psychiatry Flashcards

1
Q

what is the mechanism of action of typical antipsychotics?

A

Dopamine D2 receptor antagonists

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2
Q

Which drugs are typical anti-psychotics?

A

Haloperidol, chlorpromazine

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3
Q

Which medications are atypical antipsychotics?

A

clozapine, risperidone, olanzapine

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4
Q

what adverse effects do you get with typical antipsychotics?

A

extrapyramidal side effects and hyperprolactinaemia

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5
Q

What adverse effects do you get with atypical antipsychotics?

A

metabolic dysfunction

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6
Q

How would you manage acute dystonia?

A

procyclidine

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7
Q

What are the main side effects of tricyclic anti-depressants?

A

dry mouth and weight gain, blurred vision, constipation, urine retention

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8
Q

Name some TCAs

A

Amitryptiline, clompramine, imipramine

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9
Q

What can precipitate lithium toxicity?

A

dehydration, renal failure, diuretics, ACE-I/ARBs, NSAIDs, metronidazole

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10
Q

What are the features of lithium toxicity?

A

a course tremor, hyperreflexia, acute confusion, polyuria, seizure, coma

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11
Q

What is the management of lithium toxicity?

A

fluid resuscitation, haemodialysis

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12
Q

Which anti-depressant commonly causes QT prolongation and Torsades de pointes?

A

CitaloPRAM (babies are QTs)

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13
Q

Which anti-depressant is given to post-MI patients?

A

sertraline

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14
Q

Which anti-depressant is usually given in children and adolescents?

A

fluoxetine

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15
Q

What are the most common side effects of SSRIs?

A

GI upset
GI bleeding - must take PPI if taking with NSAIDs

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16
Q

Which drugs should you not take with SSRIs?

A

NSAIDs, warfarin/heparin, aspirin, triptans and MAOIs (^risk of serotonin syndrome)

17
Q

When should patients be reviewed after starting an SSRI?

A

2 weeks
unless high suicide risk or under 25 - 1 week

18
Q

What are the features of serotonin syndrome?

A

Sweating, tremor, confusion and hyperreflexia

19
Q

What is the management of serotonin syndrome?

A
  • IV fluids
  • benzodiazepines
  • senotonin antagonists - chlorpromazine

Finals passmed (23 decks)

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