psych-pharm Flashcards
preferred tx forEtOH WD
benzo
preferred tx for anxiety
SSRI, SNRI, buspirone
preferred tx for ADHD
menthylphenidate, amphetamines
preferred tx for bipolar
lithium, valpro, carbamazapine, atypical antupsychotic
preferred tx for for bulima
SSRIs
preferred tx for depression
SSRI SNRI, TCAs bspirone mirtazipine
preferred tx for panic disorder
SSRIs, ven;afaxine, benzos (NO BENZO IN PTSD)
preferred tx for PTSD
SSRI
preferred tx for schizophrenia
antipsychotics
preferred tx for social phobias
SSRIs
tourette’s
antipsychotics
MOA of CNS stimulants
increase catecholamines at the synaptic cleft
antipsychotic MOA
block dopamine D2 receptors
high potency antipsychotics
Trifluoperazine, fluphenazine, haldol (mostly used for + sx)
low potency antipsychotics
chloropromazine, thiorodazine (mostly used for + sx)
side effects of antipsychotics
extrapyramidal effects, galactorrhea, dry mouth, constipation, hypotension, and sedation
serious tox of antipsychotics
neuroleptic malignant syndrome, tardive dyskinesia
atypical antipsychotics
olamazapine, clozapine, quietiapine, riperidone, aripiprazile, ziprasidone
use of atypical antipsychotics
schizophrenia (+ and - sx), bipolar, OCD, anxiety, dpression, mania, tourettes
clozapine may SE
agranulytosis, weighht gain
ziprasidone may cause
proloinged QT
side effects of Lithium
tremor, Diabetes inspiidious, hypothyroidism, tetreagenic
MOA of buspirone
stimulates 5HT1a receptors
use of buspirone
generalized anxiety - does not cause tolerance, sedation, or addiction. Does not interect w/alchohol
SSRIs
fluoxetine,pratoxetine, sertaline, citalopram
time to effect for SSRI
4-8 weeks
tox if SSRIs
GI distress, sexual dysfunction, serotinin syndrome
tx of serotinin syndrome
hyperthermia, confusion, myoclunis, CV collapse, flushing, diarrhea, seizures
treatment of serotinin syndrome
cyproheptadine
SNRI MOA
inhibits serotonin and NE uptake
SNRI examples
venlaxafine, duloxatine
duloxatine use
depression and diabetic neuropathy
tox of SNRIs
raised BP, stimulation, nausea
TCA examples
amytriptyline, -iptykine, or -ipramine, doxepin, amoxapine
MOA of TCAs
block reuptake of NE and serotinin
clinical use of TCAs
depression, bedwetting (imipramine), OCD(clomipramine) fibromyalgia
tox of TCA
sedation, alpha1 blocking effects,anticholinergic effects, arrythmias,
TCA effects in elderly
confusion and hallucinations
MAOis
phenelzine, isocarboazid, selegiline
use of MAOis
atypical depression, anxiety, hypochondrias
tox of MAOis
hypertensive crisis (with cheese of whine) CNS stimulaton
interacts with MAOis
SSRIs, TCAs, st john’s wort, meperidine, dextromethorphan
use of bupropion
depression, smoking sensation
tox of bupropion
stimulant effects, headache, seizure in bulimics
mirtzapine MOA
a2 antagonist (increases release of NE and serotonin) and potent 5-HT2/3 antagonist
tox of mirtazapine
increased appitite, weight gain (might be the point - used in anorexia)