Proteins - Lecture Three Flashcards
Proteins and Cellular Function
Proteins
Are non-branching polymers that form macromolecules about 50-100 x 10-10 m in size
What are proteins composed of?
A specific sequence of amino acids joined together by chemical bonds called peptide bonds
How many different amino acids are used to make proteins
20
Depicting the protein structure
Protein crystallography
Electron cryo-microscopy
NMR spectroscopy
Depicting the chemical structure of a protein
Skeletal
Ball and stick
Space-filling
Cell signalling hormone
Insulin
Insulin
After a meal, insulin is generated and binds to the insulin receptor to signal cells to take up glucose
Metabolism and digestion
Alcohol dehydrogenase
Alcohol dehydrogenase
Helps to metabolise ethanol
Hexokinase
Adds phosphate to glucose, after glucose is taken up by the cell
Oxygen transport metabolism
Haemoglobin
Haemoglobin
Binds oxygen in the lungs and carries it in the blood to tissues for use in metabolism
Protein digestion
Trypsin
Trypsin
Breaks down proteins during digestion
Immune protection
Antibody