Metabolism - Lecture Twenty-Nine

Question 1

Excess energy consumed as glucose

Answer 1

Stored as fat

Question 2

Fatty acids are preferred

Answer 2

As fuel for most tissues under normal conditions

Question 3

Why store fuel as fats?

Answer 3

Fatty acids are more reduced than carbohydrates

Question 4

Where is TAG stored?

Answer 4

In adipose tissue

Question 5

How do we get TAG back in the form of energy?

Answer 5

Signals activate a class of enzymes called lipase. The lipase cleave the FFA (free fatty acids)

Question 6

Why are fatty acids activated?

Answer 6

For oxidation

Question 7

When are fatty acids activated?

Answer 7

Before the fatty acid enters the mitochondria

Question 8

How are fatty acids activated?

Answer 8

By attachment to CoA making fatty acyl-CoA

Question 9

The fatty acyl-CoA must pass through two membranes

Answer 9

Outer membrane through the fatty acyl-CoA carrier

Inner membrane which requires the conversion to fatty acyl-carnitine

Question 10

Beta-Oxidation

Answer 10

Uses fatty acids with an even number of carbons that are saturated and cuts carbon chains into 2 carbon pieces

Question 11

Beta-Oxidation and ATP

Answer 11

No ATP is made in beta-oxidation

Question 12

Energy released in beta-oxidation is transferred to?

Answer 12

The coenzymes NAD and FAD

Question 13

The product of beta-oxidation

Answer 13

Acetyl-CoA

Question 14

Reaction one of beta-oxidation

Answer 14

Oxidation of FAD to FADH2

Question 15

Reaction two of beta-oxidation

Answer 15

Hydration (addition of H2O)

Question 16

Reaction three of beta-oxidation

Answer 16

Oxidation of NAD+ to NADH, H+

Question 17

Number of rounds =

Answer 17

n(C)/2 - 1