Metabolism - Lecture Thirty-One Flashcards
Oxidation of Amino Acids
1
Q
What part of the amino acid do we extract energy from?
A
Carbon-skeleton
2
Q
Transamination
A
Amino acids transferring their amino group to a keto acid, this is catalysed by aminotransferase
3
Q
Pyridoxal phosphate
A
Co-enzyme required for transamination reactions that accepts the amino group from the amino acid and transfers it to the keto acid
4
Q
Two forms pyridoxal phosphate exists as
A
Pyridoxal phosphate (no amino group) Pyridoxamine phosphate (with amino group)
5
Q
What is pyridoxal phosphate derived from?
A
Vitamin B6
6
Q
First step of pyridoxal phosphate
A
Amino group is transferred from the amino acid to the pyridoxal phosphate
7
Q
Second step of pyridoxal phosphate
A
Amino group is transferred pyridoxine phosphate to the keto acid
8
Q
Amino acid, glutamate ⇄
A
Keto acid, alpha-ketoglutarate
9
Q
Amino acid, aspartate ⇄
A
Key acid, oxaloacetate
10
Q
Amino acid, alanine ⇄
A
Pyruvate
