Metabolism - Lecture Twenty-Eight Flashcards
Glycolysis
Glucose oxidised
During glycolysis
Where do glycolysis occur?
Usually in the cytoplasm
How much glucose per day does the human brain require?
120g
What do white blood cells tend to use as fuel?
Glucose
What do red blood cells tend to use as fuel?
Fats
Too much acetyl CoA in glycolysis
Will stop the pyruvate dehydrogenase reaction
Activation of glucose in the Energy Investment Phase
Getting the molecule into a form so that energy can be captured
Energy Payoff Phase
Return on the investment by making an ATP profit
The two phosphorylation reactions of ADP to ATP
Substrate-level phosphorylation
Oxidative phosphorylation
Substrate-level phosphorylation
Direct
Energy comes from substrate
Two key types of reactions for processing food molecules for ATP synthesis
Phosphorylation of ADP to ATP
Redox reactions
Kinase
Named for reverse reaction
Fates of pyruvate - anaerobic conditions
In animals, pyruvate is converted to lactate in anaerobic conditions
In yeast, pyruvate is converted to ethanol and CO2 and also recycles NAD+
Anaerobic metabolism allows for the regeneration of NAD+
Glycolysis can continue as there is sufficient NAD+ for the next reaction