Metabolism - Lecture Thirty-Five Flashcards
Membrane Receptors and Cell Signalling
Why do we need food stores?
The body cannot store ATP, therefore fuel to make ATP must be stored instead
Fat storage
Triacylglycerols that are stored as fat droplets in adipose tissue. Excess fat and carbohydrate from diet can be converted to stored fat as we have unlimited fat stores
Tri-acyl-glycerol
Three-fatty acids-glycerol
Double bond in a triacylglycerol
You get a kink in the fatty lipid chain. The kinking affects the fluidity of the phospholipid membranes
Synthesis of triacylglycerols
Stimulated by insulin
Synthesis of triacylglycerols - Fatty acids from
Chylomicrons
Synthesis of triacylglycerols - Glycerol backbone from
Glucose
Synthesis of triacylglycerols - Activation of fatty acids to
acyl-CoA
Where does the glycerol phosphate come from?
From glycolytic pathway
Mobilisation of triacylglycerols
Hydrolysis of TAGs catalysed by hormone-sensitive lipase
What is the mobilisation of triacylglycerols stimulated by?
Hormones: adrenaline and glucagon
What does mobilisation of triacylglycerols release?
Free fatty acids and glycerol
Glycogen
Branched polysaccharide, α, 1-4 and α, 1-6 glycosidic bonds
Where is glycogen stored?
Liver and muscle
Where are glycogen granules?
Cytoplasm
