Metabolism - Lecture Twenty-Two Flashcards
Energy Balances in Cells and Organisms
First Law of Thermodynamics
The total energy within a system is constant, where energy can neither be created or destroyed but can be converted
Eintake =
Eexpended + Estored (weight gain)
Weight loss can be achieved by
Reducing energy intake (eat less and/or take certain drugs)
Increasing activities
Increasing basal metabolism (the energy required for maintenance of life)
Units of energy
Joules (J)
Direct calorimetry
Relies on measuring heat output from individual but good for determining basal metabolic rate
Indirect calorimetry
Based on O2 consumption and CO2 production measured using a respirometer
RER =
CO2 produced / O2 consumed
Basal metabolism
Energy required to the maintenance of life
Energy required to the maintenance of life
Muscle contraction Nerve conduction Ion transport Synthesis of macromolecules Maintenance of body heat
Factors that affect basal metabolism
Gender Age Hormonal status Stress levels Disease status Certain drugs
Increase in basal metabolism by
Athletic training Late stages of pregnancy Fever Drugs e.g. caffeine Hyperthyroidism
Decrease in basal metabolism by
Malnutrition
Sleep
Drugs e.g. beta blockers
Hypothyroidism