proteins III Flashcards
most abundant in coagulation factors
a. complement
b. fibrinogen
c. transferrin
d. lipoproteins
Fibrinogen
- one of the largest protein in the plasma
- most abundant in coagulation factors
- one of APR , markedly increase during inflammatory process
marker for long tern prognosis of cardio vascular disease
a. complement
b. fibrinogen
c. transferrin
d. lipoproteins
Fibrinogen
- one of the largest protein in the plasma
- most abundant in coagulation factors
- one of APR , markedly increase during inflammatory process
- marker for long tern prognosis of cardio vascular disease
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high levels may cause elevated ESR
a. complement
b. fibrinogen
c. transferrin
d. lipoproteins
Fibrinogen
- one of the largest protein in the plasma
- most abundant in coagulation factors
- one of APR , markedly increase during inflammatory process
- marker for long tern prognosis of cardio vascular disease
- high levels may cause elevated ESR
- increase: BIRTH CONTROL, pregnancy , inflammatory disease
proteins that participates in immune reaction and serve as link to the inflammatory response
a. complement
b. fibrinogen
c. transferrin
d. lipoproteins
complement
- one of the natural defense mechanism
- it circulates as non functional precursors
- C3 is the most abundant form in serum
used as early warning test to persons at risk of coronary artery disease
a. complement
b. fibrinogen
c. CRP
d. lipoproteins
C reactive protein
- is a member of pentraxin protein family
- binds to C polysaccharide of the pneumococci
- appears in the blood of the patients with DIVERSE INFLAMMATORY DISEASE
- used as EARLY WARNING TEST to persons at risk of coronary artery disease
PROTEINS THAT IS RAPID TEST FOR PRE SUMPTIVE DIAGNOSIS OF BACTERIAL VERSUS VIRAL INFECTION
a. complement
b. fibrinogen
c. CRP
d. lipoproteins
C reactive protein
- is a member of pentraxin protein family
- binds to C polysaccharide of the pneumococci
- appears in the blood of the patients with DIVERSE INFLAMMATORY DISEASE
- used as EARLY WARNING TEST to persons at risk of coronary artery disease
- RAPID TEST FOR PRE SUMPTIVE DIAGNOSIS OF BACTERIAL VERSUS VIRAL INFECTION
a small heme protein found in skeletal and cardiac muscle
a. myoglobin
b. troponin
c. BNP
d. Cystatin C
Myoglobin
- a small heme protein found in skeletal and cardiac muscle
- it is one of the marker to diffuse out of ischemic muscle cells
- a marker for CHEST PAIN and EARLY DETECTION of AMI
useful marker for monitoring the success or failure of reperfusion
a. myoglobin
b. troponin
c. BNP
d. Cystatin C
myoglobin
- useful marker for monitoring the SUCCESS OR FAILURE OF REPERFUSION
- it is one of the marker to diffuse out of ischemic muscle cells
- a marker for CHEST PAIN and EARLY DETECTION of AMI
which of the 3 complex of troponins binds to calcium ions that regulate muscle contraction
a. TnC
b. TnI
c. Tnt
TnC , TnI, TnT
- present in both cardiac and skeletal muscles
TnC
- binds tocalcium ions that regualted muscle contractions
Tni and TnT
- cardiac marker that depend on antibodies and calibrators
Most important marker for CARDIAC INJURY (AMI)
a. myoglobin
b. troponin
c. BNP
d. Cystatin C
TROPONIN
- they are regulators of ACTIN AND MYOSIN
- MOST IMPORTANT MARKER FOR CARDIAC INJURY (AMI) - they are derived from heart muscles
- the levels of blood may elevate after AMI attack in the absence of CK-Mb elevations
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which of the 3 complex of troponins is useful in assessment of early and late AMI
a. TnC
b. TnI
c. Tnt
troponin T(TnT)/ tropomyosin binding subunit
- specific for HEART MUSCLES
- VALUABLE TOOL in diagnosis of AMI
- assessment of early and late AMI; elevated in Renal disease amd muscular dystrophy
- sensitive marker for UNSTABLE ANGINA
- Use for monitoring the effectiveness of THROMBOLYTIC THERAPY IN AMI PATIENTS
which of the 3 complex of troponins is Use for monitoring the effectiveness of THROMBOLYTIC THERAPY IN AMI PATIENTS
a. TnC
b. TnI
c. Tnt
troponin T(TnT)/ tropomyosin binding subunit
- specific for HEART MUSCLES
- VALUABLE TOOL in diagnosis of AMI
- assessment of early and late AMI; elevated in Renal disease amd muscular dystrophy
- sensitive marker for UNSTABLE ANGINA
- Use for monitoring the effectiveness of THROMBOLYTIC THERAPY IN AMI PATIENTS
which of the 3 complex of troponins is highly specific for AMI
a. TnC
b. TnI
c. Tnt
Troponin I (TnI) / inhibitory subunit or actin binding unit
- only found in MYOCARDIUM
- GREATER CARDIAC SPECIFCITY than TnT
- HIGHLY SPECIFIC for AMI - not elevated in renal disease
- very sensitive indicator of even minor amount of cardiac necrosis
