MAJOR CLINICAL ENZYMES Flashcards

1
Q

which of the following enzymes is for pancreas

a. CK-MB
b. amylase
c. lipase
d. acp

A

pancreas
- Amylase
lipase

(Lola Amy Perez)

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2
Q

which of the following enzymes is for heart

a. CK-MB
b. amylase
c. lipase
d. acp

A

heart
ck- mb
ast
ld1>ld2

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3
Q

which of the following enzymes is for prostate

a. CK-MB
b. amylase
c. lipase
d. acp

A

prostate

- ACP

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4
Q

which of the following enzymes is for biliary cirrhosis

a. CK-MB
b. amylase
c. lipase
d. acp

A
liver
  > hepatocellular disorder 
           ast
           alt
           Ld5

> biliary obstruction
ALP
GGT

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5
Q

sensitive indicator of AMI and Duchenne type muscular dystrophy

a. CK
b. LD
c. ACP
d. AST

A
creatinine kinase
  -  frequently elevated in disorders of CARDIAC AND SKELETAL MUSCLES
  -  sensitive indicator of AMI AND DUCHENNE TYPE  MUSCULAR DYSTROPY
  -  pronounced elevation
      duchenne muscular dystropy
      polymyositis
      dermatomyositis
      myocardial infarction
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6
Q

what is the forward reaction on CK

a. oliver rosalki
b. tanzer gilvarg
c. wacker et al
d. wrobleuski la due

A

creatinine kinase
> forward - tanzer gilvarg (pH 9.0)

> reverse - oliver rosalki (pH 6.8)
- more commonly performed

lactate dehydrogenase
> forward - wacker et al
> reverse - Wrobleuski la due

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7
Q

lactate dehydrogenase
Each isoenzyme is composed of 4 subunits. the subunits are 2 different structure: ______ and ______

a. liver
b, brain
c.muscles
d. heart

A

Each isoenzyme is composed of 4 subunits. the subunits are 2 different structure: H (HEART) AND M (MUSCLES)

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8
Q

what is the enzyme highest in PERNICIOUS ANEMIA AND HEMOLYTIC DISORDERS

a. GGT
b. CK
c. LD
d. AST

A

lactate dehydrogenase

  • widely DISTRIBUTED in the TISSUE of the body
  • HIGH CONCENTRATION on heart and liver
  • HIGHEST LEVEL OF LDH ARE SEEN IN PERNICIOUS ANEMIA AND HEMOLYTIC DISORDERS
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9
Q

which of the LD isoenzyme has the highest serum concentration

a. LD1
b. LD2
c. LD3
d. LD4

A

according to concentration

LD2 > Ld1 > LD3 > LD4 > LD 5

LD2 
  - highest serum concentration 
  -  major isoenzyme in healthy people
  - LD2> LD1  =   healthy persons
  LD1 >  LD2  = flipped pattern
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10
Q

which of the following isoenzyme has a disorder of acute pancreatitis

a. LD1
b. LD2
c. LD3
d. LD4
e. LD5

A
LD 3 (HHMM)
 tissue :  lungs,  lymphocytes  .  spleen   and pancrcease
 disorder  :  PELAC
  pulmonary embolism
  extensive pulmonary pneumonia
  lymphocytosis
  acute pancreatitis
  carcimona
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