Proteins Flashcards
What order of protein structure refers to the order of the sequence of amino acids?
Primary
What order of structure refers to the spatial arrangement of polypeptides in a multi subunit protein?
Quaternary
What is the tertiary structure of a protein?
Spatial arrangement of amino acid residues that are far apart in a linear sequence
What are the two types of secondary structures of a polypeptide?
Alpha helix
Beta pleated sheet
What causes an alpha helix to form?
Hydrogen bonds between N-H and C=O groups
What amino acid is responsible for disulphide bridge formation?
Cysteine
What is glycosylation?
Post-translational modification converting a protein into a glycoprotein
(Protein + carbohydrate)
Where does glycosylation take place in a cell?
ER and golgi apparatus
What is a lipoprotein?
Protein + lipid
Either covalent or non-covalently joined
What is the main use of lipoproteins?
Transport of fats and cholesterol in blood
What is a metalloprotein?
Protein molecule with a metal ion bound to it
What are functions of globular proteins? (5)
Enzymes
Transporters
Messengers
Stock of amino acids
Some structural function - actin etc
What are fibrous proteins generally used for? (4)
Bone matrices
Muscle fibres
Tendons
Connective tissue
Membranous proteins are found on cell membranes and organelle membranes. What are they used for? (4)
Relay signals
Transporters
Enzymes
Cell - cell joining
What type of protein is collagen, and what is used for?
Fibrous
Structural shit