prostate cancer

Question 1

what is the msot common solid organ cancer in men

Answer 1

prostate cancer

Question 2

sx associated with early prostate cancer

Answer 2

NONE

Question 3

high risk grp to screen before age 55

Answer 3

AA race, famhx

Question 4

screening in age 55-69

Answer 4

shared decision marking

Question 5

screening in men >70

Answer 5

no screening

Question 6

normal PSA

Answer 6

under 4 ng/ml

Question 7

what percentage of suspicious palpable lesions are proven to be cancer

Answer 7

> 50%

Question 8

PSA & DRE are ____, not _____for prostate cancer. proceed with___

Answer 8

PSA & DRE are indications, not diagnostic for prostate cancer. proceed with biopsy

Question 9

indications for prostate biopsy

Answer 9

abnormal DRE and/or PSA

Question 10

most prostate cancer are___, and found in which zone?

Answer 10

adenocarcinoma; peripheral zone

Question 11

risk stratification is assigned by what factors (3)

Answer 11

1. PSA
2. Gleason score/pathology from biopsy
3. staging

Question 12

who is a candidate for watchful waiting?

Answer 12

low grade disease or low volume disease

Question 13

what consists of active surveillance?

Answer 13

DRE & PSA every 3-6 months + repeat prostate biopsy every 1-2 yrs

Question 14

gold standard for localized disease

Answer 14

radical prostatectomy

Question 15

where does prostate cancer metastasize to?

Answer 15

pelvic LN, bone, lung, liver

Question 16

what type of lesion does metastatic prostate cancer cause in bone?

Answer 16

osteoblastic lesion

Question 17

use of hormonal tx is ____, not ____

Answer 17

palliative, not curative

Question 18

tx for hormone refractory prostate cancer

Answer 18

systemic chemotx

Question 19

what to do if you have an abnormality of either screening tool?

Answer 19

referral to urologist

Question 20

tx for metastatic prostate cancer

Answer 20

androgen deprivation