chronic kidney disease Flashcards

1
Q

CKD is defined by presence of kidney damage for how long?

A

3+ months

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2
Q

decr kidney fxn is defined as eGFR under_____per 1.73 m^2

A

60 ml/min

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3
Q

prevalence of CKD

A

1/10

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4
Q

ESRD is more prevalent in whites or blacks

A

Af Am

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5
Q

gold standard to measure GFR

A

inulin

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6
Q

compensatory incr in filtration in the preserved nephron

A

glomerular hyperfiltration

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7
Q

presence of nitrogenous waste products in the blood

A

azotemia

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8
Q

azotemia + S/S that are a result of renal failure

A

uremia

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9
Q

number 1 complication related to CKD

A

cardiovascular

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10
Q

extraosseous calcification characterized by systemic medial calcification of the arterioles that leads to ischemia and subcutaneous necrosis.

A

calciphylaxis

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11
Q

stage 1 tx

A

tx comorbid conditions, aim to slow progression

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12
Q

stage 2 tx

A

estimate progression

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13
Q

stage 3

A

evaluate and tx complications

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14
Q

stage 4 tx

A

prepare for kidney replacement tx

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15
Q

stage 5 tx

A

dialysis

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16
Q

target BP in CKD

A

under 140/90

17
Q

target urine albumin in CKD

A

under 30 mg per 24 hrs

18
Q

if urine albumin is >30, then what is bp goal?

A

under 130/80

19
Q

salt intake should be under____per day

A

90 mmol

20
Q

patients with GFR under____ are prone to incr_____

A

under 15 (stage 5); incr ECF

21
Q

anemia is dx’d in CKD in males at Hb_____, in females_____

A

males Hb under 13

females Hb under 12

22
Q

how often to check for anemia in stage 1-2

A

when clinically indicated

23
Q

how often to check for anemia in stage 3

A

annually

24
Q

how often to check for anemia in stage 4,5

A

2x/year

25
Q

goal Hb with tx in CKD

A

10-11 g/DL

26
Q

what is the #2 cause of death in CKD

A

malnutrition

27
Q

what endogenous substance is a uremic toxin

A

PTH

28
Q

goal for phosphorus levels

A

keep (Ca)(P) below 55

29
Q

when should you use caution with radiocontrast in CKD

A

GFR under 60

30
Q

when is it contraindicated to use gadolinium based contrast in CKD unless no alternatives

A

GFR under 15

31
Q

when should you offer macrocyclic chelate preparation to use gadolinium based contrast in CKD

A

GFR under 30

32
Q

risk of gadolinium based contrast in CKD

A

nephrogenic systemic fibrosis