Principles Of Protein Folding

Question 1

What is buried on the interior of proteins?

Answer 1

Hydrophobic interactions

Question 2

How are salt bridges / ionic bonds formed?

Answer 2

They are formed by basic and acidic amino acids

Question 3

How are disulfide bonds formed?

Answer 3

Bonds- cysteines

Question 4

What are chaperonins?

Answer 4

Protein molecules that assist in the proper folding of other proteins

Question 5

What are some examples of protein denaturation?

Answer 5

Disruption of h-bonds, ionic bonds, alteration of 2-d and 3-d structure and destruction of functionality

Question 6

Give an example where a change of structure led to an entire change of function

Answer 6

Change of glu to Val changed a normal cell to a sickle cell

Question 7

. What are some things that lead to protein denaturation??

Answer 7

Temperature, ph and salinity

Question 8

What kind of bond is exposed on the surface of proteins?

Answer 8

Hydrogen bonds/ hydrophilic interactions

Question 9

How are disulfide bridges formed?

Answer 9

Amino acids from sulfur