Genetics Flashcards

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1
Q

Who is the father of genetics?

A

Gregor Mendel

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2
Q

What is the principle of independent assortment?

A

Where the inheritance of one trait has no effect on the inheritance of another trait.

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3
Q

What are homozygous in terms of alleles?

A

Same alleles

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4
Q

What are heterozygous in terms of alleles?

A

Different alleles

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5
Q

What is a dihybrid cross?

A

Study of 2 characteristics from parents

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6
Q

What is monohybrid cross?

A

Study of one characteristic from each parent

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7
Q

How does meiosis explain mendel’S principle?

A

Two equally probable arrangements at Metaphase I give rise to different chromosome combinations

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8
Q

What are the patterns of inheritance?

A

Dominant and recessive, incomplete dominance, co dominance , polygenetic inheritance, epistaxis and sex-linked genes

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9
Q

Explain dominant and recessive genes?

A

Either you get them or you don’tfor recessive and you can only get them with two recessives crossing over

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10
Q

What kind of pattern of inheritance do heterozygous show an intermediate phenotype?

A

Incomplete dominance

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11
Q

What kind of pattern of inheritance are there 2 or more alleles that are dominant in the phonotype with both being expressed and not mixed?.

A

Codominance

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12
Q

What is an Rh factor?

A

A factor found on red blood cells

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13
Q

What does Rh+ mean?

A

Protein

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14
Q

What does Rh- mean?

A

No protein

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15
Q

What are some phenotypes determined by?

A

Additive effects of 2 or more genes on a single characteristic with phenotypes on a continuum

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16
Q

What is pleitrophy?

A

A gene whose product influences multiple traits

17
Q

What are some complex genetic disorders?

A

Cystic fibrosis, marfan syndrome and sickle-cell anemia

18
Q

What is it called when alleles for one gene alter the effects of another gene?

A

Epistasis

19
Q

What gender is affected mostly by sex linked disorders and why?

A

Men because they only have one x-chromosone

20
Q

How does a father pass down a sex-linked disease?

A

He will pass it down to of all his daughters who either be carriers or just affected

21
Q
  • what are some x linked sex disorders?
A

ALD, hypertrichosis, hemophilia, color blindness

22
Q

What factors influence phenotype?

A

Genetic and environmental

23
Q

What is a pedigree?

A

A family tree that describes the inter-relationships of parents and children across the generations

24
Q

What can be traced and described using pedigrees?

A

Inheritance patterns ofparticular traits

25
Q

What are autosomal recessive traits?

A

When the trait can skip generations, inbreeding increases it and affects males and females equally

26
Q

What are some autosomal recessive traits?

A

Cystic fibrosis, tay -Sach’s disease and sickle-cell anemia

27
Q

How are autosomal dominant pedigrees passed down?

A

Only about half of individuals get trait regardless of their sex

28
Q

How do x-linked recessive pedigrees behave?

A

They skip generations, affected fathers do not pass down to their sons and males are more often affected

29
Q

How do x-linked dominant diseases behave?

A

Everyone gets in when the mother has it , males and females are equally affected and they are extremely unusual