Principles 3 Flashcards
soma
cell body
dendrite
etends from body
receives signal information from local environment
associated with receptors that are designed to sense specific stimuli or react to specific chemical transmitters
axon
signals which travel as action postentials are generated here
action potential
summation of signals received from dendrites, which can either be stimulatory or inhibitory
when it reaches the end of the axon it causes the release of a neurotransmitter
2 factors for action potential speed?
diameter and degree of myelination
oligodendrocytes
produce myelin in CNS
multiple sclerosis is demyelination of oligodendrocytes
schwann cells
insulate nerve fibers; produce myelin in PNS
guillian-barre (demyelination of PNS)
describe DRG pathway
cell bodies in DRG
each DRG contains peripheral process, which extends to the periphery along the path taken by the spinal nerve and its branches, and a central process, which etends into the CNS as the dorsal root of the spinal nerve
mechanoreceptors
touch, hearing
detect pressure, lengthening, compression, tension
thermoreceptors
temperature
nociceptors
pain
chemoreceptors
smell, taste
electromagnetic
vision
alpha motor neurons
innervate and activate skeletal muscle fiber through myoneural junction
large diameter, fast conducting
acetylcholine
gamma motor neurons
innervate intrafusal muscle fibers which are a component of muscle spindles
establish a set point for muscle tone
type 1 receptors
confined to the outer layers of the joint capsule and are stimulated by active or pasive joint motion
describe the firing rate and threshold for type 1 receptors
firing rate is inhibited with joint approximation
low threshold, making them very sensitive to movement
stimulation of type 1 is involved with?
reflex modulation of posture, as well as movement, through conttant monitoring of outer joint tension
perception of posture and movements
inhibition of flow from pain receptors via enkephalin synaptiv interneuron transmitter
tonic effects on LMN pools involved in neck, limbs, jaw and eye muscles
type 2 mechanoreceptors
found within the deeper layers of joint capsule. low threshold and stimulated with minor changes in tension wihin the inner joint
adapt rappidly and quicly cease firing when the joint stops moving
completely inactive in immobilized joints
functions of type 2 mechanoreceptors
monitor direction of movement
creaste a relfex effect on segmental muscle tone, providing a “braking mechanism” against movement that overdisplaces the joint
recognize potensially harmful movements
type 4 receptors
composed of a network of free nerve endings, as well as unmyelinated fibers.
pain perception, itch and tickle
close to mechanoreceptors
high threshold, completely unactive in the physiologic joint
basic function of type 4 receptors
evocation of pain
tonic effects on neck, limb, jaw, eye muscles
central relfex connections for pain inhibition
central relfex connections for a myriad of autonomic effects
gate theory
when mechanoreceptors function correctly, nociceptors are inhibited
when mechanoreceptors function incorrectly, nociceptors are inhibited les
rubrospinal
muscle tone and synergy to proximal flexors of the upper extremities
reticulospinal
muscle tone and synergy to the voluntary extensor muscles of the bacck and arms
tectospinal tract
neck extensor muscles and eye muscle
vestibulospinal tract
extensor muscles of back and legs
balances reflexes and postural muscles
corticospinal (pyramidal)
voluntary motor
flexors of teh hands and feet
lateral vs ventral spinothalamic tract
lateral: pain and temperature
ventral: crude touch and pressure
dorsal columns medial lemniscus
carry conscious proprioception
vibration, joint position sense, 2 point discrimination
receptors of dorsal columns medial lemniscus
meissner’s/merkel
pacinian
ruffini
meissner’s merel’s
touch
pacinian
vibration
ruffini
joint postion sense
spinocerebellar pathway
carry unconscious proprioception
muscle spindle cell: type 1a fibers- stretch
golgi tendon organ: type 1b fibers- tension
describe how the adjustment affects the a alpha 1b golgi tendons. what happens after that?
stimulate the a alpha 1b golgi tendons
postsynaptic inhibition of the alpha motor neurons (innervate skeletal muscles) due to fast stretch on the tendon
how does the adjustment affect the pain gait?
closes the pain gate by sending proprioceptive message to the CNS on the large type A fibers
describe the other stuff that is affected by the adjustment
increase mechanoreceptor bombardment (closes pain gate) touch can decrease pain
break up adhesions
increase mobility/motion
improve neurological function
C1
global function systemic effects
C2/3
tonsils
T1-4
heart and lung
T4
gallbladder
T5-9
stomach
T6-10
liver, pancreas, gallbladder
T10-12
kidney
L1-2
ovary, colon (sympatheticallly driven)
sacrum
colon, uterus
parasympathetically driven