Prep 3 Flashcards
What is GH normally supressed to after OGTT?
<2
in acromegaly no suppression
exclamation mark hair
allopecia areata
single crease on nose
chronic rubbing
white spots on soft palate and ear pain
ramsey hunt
PE in pregnancy
LMWH
CURB 65
confusion urea >7 RR >30 BP <90 or <60 65 years 0-2 amox 5days 3-5 IV co-amox + PO doxy 7days
endocarditis IVOST
always requires IV no oral switch
addisons
primary adrenal insufficiency
AI destruction most common cause
normal endometrial thickness
<4mm
risk factors for endometrial cancer
nulliparous diabetic early menarche, last menopause unoposed oestrogen tamoxifen (although antagonistic to breast tissue can be agonistic at other sites) PCOS
what is tamoxifen and hat is it used for
selective oestrogen receptor modulator
oestrogen receptor positive breast ca (typically continues for 5 years post surgery)
colposcopy shows ulcerated lesion with discharge
LLETZ
what are the main types of shock
Septic Haemorrhagic Neurogenic Cardiogenic Anaphylactic
diagnosing sepsis
sews > 4 or infection likely
SIRS >2
SIRS
RR > 20 change in mental state temperature <36 >38 known/suspected neutropenia HR >90 WCC <4 >12
assessing organ dysfunction in sepsis
systolic BP <90 or <40 below norm or MAP <65
urine output <30 for 24 hrs
lactate <4
newly altered mental state
new need for O2
serum creatinine >150
unexplained coagulopathy/thrombocytopenia
SEPSIS 6 management
take blood cultures, lactate and urine output
give O2, fluids and abx
pathophysiology of drowning
conscious breath hold until hypercapnia triggers breathing reflex
fluid aspiration or into stomach if laryngospasm
cerebral anoxia (hypoxemia and acidosis)
irrevesible cerebral damage
What happens with inhalation of fresh water
hypervolemia, hyponatatremia, hpyerkalemia (fresh water is hypotonic and hyponatremic so causes osmotic diffusion of water into blood and sodium into alveoli)
motorcycle accident, airway clear and breathing ok but weak radial pulse what kind of shock
haemorrhagic
fluid administration followed by rapid deterioration
stop fluids
IV furosemide
dose of adrenaline in anaphylaxis
0.5ml 1g:1000ml IM (1mg:1ml)
dose of adrenaline in cardiac arrest
1ml 1:1000 IV
what does a 100% solution mean
1gram of drug for 1ml of vol
how many mg in a g
1000
how many mcg in a mg
1000
What does a 1% solution mean
1g in 100ml
bradycardia with adverse features (shock, syncope, myocardial ischamia, hf)
atropine 500mcg IV
hepatoxic drugs
paracetamol and NSAIDs
SABA + ICS step up
SABA + beclamethasone and falmeterol combo inhaler
Centor criteri
cough absent
exudate
nodes
temperature >38
why does trimethorpim not work in upper UTI
doesnt penetrate renal parenchyma