PoxViruses Flashcards

1
Q

resistance of poxvirus

A

High (in scabs)

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2
Q

what are called the poxvirus intracytoplasmic acidophilic inclusion bodies in mammals

A

Guarnieri body

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3
Q

what are called the poxvirus intracytoplasmic acidophilic inclusion bodies in birds

A

Bollinger body

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4
Q

Which poxvirus genus is zoonotic

A

Orthopox
Parapox

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5
Q

Parapoxvirus genus

A

Bovine papular stomatitis, contagious pustular dermatitis, pseudocowpox, seal pox

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6
Q

PoxVirus pathogenesis

A

aerogenic, PO, contact, arthropods
Primary rep locally
1. stadium erythematosum (reddened)
2. stadium papulosum (proliferatio, grey nodule)
3. stadium vesiculosum (cell necrosis, vesicle)
4. stadium pustulosum (pus)
5. stadium crustosum (dry crust)
6. stadium decrustationis (crust peel off)
7. recovery (with or without scar)

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7
Q

which pox virus does not give a life long immunity?

A

Parapoxvirus

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8
Q

PoxVirus vaccine

A

live virus vaccine

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9
Q

attenuated poxvirus vaccine is against which disease

A

myxomatosis

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10
Q

cowpox causative agent

A

cowpox virus

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11
Q

cowpox carriers

A

rodents (25% seropositive)

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12
Q

cowpox route of infection

A

contact, wounds

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13
Q

cowpox epizootiology

A

rarely in cattle
entire stock is affected
immunity for years
zoonotic

from cattle to rat

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14
Q

cowpox CS

A

mild fever, papules at inf. site
Rarely generalized
Haemorrhagic, red/black pustules, papules, (only rarely vesicles): udder, mouth, scrotal skin

not often generalized

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15
Q

Cowpox recovery time

A

approx. 1 month

longer in poor hygiene conditions

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16
Q

cow pox differential

A

Herpes mamillitis

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17
Q

cowpox in other animals

A

rodents: subclinical, around the mouth
feline: asymptomatic or legs, upper resp symptoms
Hu: milking nodules on hands (immune suppresed can become generalized)
elephant, seal: generalized

18
Q

smallpox infect naturally

A

only people

19
Q

Variola major variants

A

Skin changes, generalized disease: 45% mortality,
The haemorrhagic form: 100% mortality

20
Q

variola higher mortality in which age group

A

young

21
Q

variola vaccination in 1700s

A

with cowpox, farmers & milkmaids suffered less from smallpox

22
Q

smallpox occurence

A

Earth is free from the 8th of May 1980

23
Q

Monkeypox occurence

A

endemic in central and west africa

24
Q

monkeypox occurence

A

endemic in central and west africa

25
Q

how lethal is monkeypox in humans

A

used to be 30% now lower due to small pox vaccination

26
Q

2022 monkeypox pandemic

A

almost only among bi- & homo-sexuals

27
Q

Pseudocowpox’s virus from which genus

A

parapox genus

28
Q

pseudocowpox infects

A

cattle & humans: Zoonotic

29
Q

pseudocowpox in cows

A

mild, disease on udder and teat
introduction of infected animals, infection by contact (hands, milking cups)

30
Q

pseudocowpox symptoms

A

lesions on udder and teat
serous exudate on surface of papules

incubation 1 week

short immunity = recurrent disease

31
Q

Bovine papular stomatitis infects what age group

A

mostly calves under 1 year old, but occurs at any age

32
Q

Bovine papular stomatitis immunity lasts for how long

A

short term

33
Q

Bovine papular stomatitis clinical symptoms

A

mucosal membranes, redness, papules (heals after few weeks)
no fever, no other symptoms, but can be painful => weight loss

34
Q

Bovine papular stomatitis zoonotic?

A

yes

35
Q

Bovine papular stomatitis vaccine

A

none

36
Q

Contagious pustular dermatitis causative agent

A

Orf virus

37
Q

Orf virus resistancy

A

highly resistant

(12 yrs in dried crust)

38
Q

Contagious pustular dermatitis affects which animals

A

sheep, goat, humans
mass disease in young lambs (after lambing season)

zoonotic

39
Q

Contagious pustular dermatitis pathogenesis

A

route of infection: mouth and foot injuries caused by rough feed
papules, serous exudates, crusts

40
Q

Contagious pustular dermatitis CS

A

lesions lips, feet, udder, prepuce
painful: no grazing, weight loss
rarely papules in internal organs (GI, lungs & heart)

41
Q

Contagious pustular dermatitis vaccine

A

protects for 6 months:
- Vaccine containing virulent virus: scarified into the skin in case of an outbreak
- Attenuated virus: in injectable form, can also be used in non-infected herds (no viral shedding)