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Epi MT > Orthoreoviruses, Avian reovirus and Rotavirus > Flashcards

Orthoreoviruses, Avian reovirus and Rotavirus Flashcards

1
Q

What does REO stand for?

A

resp
enteric
orphan

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2
Q

Reo virus genotype

A
  • dsRNA
  • highly resistant
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3
Q

T/F

Avian Orthoreovirus is species specific virus

A

False

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4
Q

reo virus genus

A

orthoreovirus
rotavirus
OrbiVirus (BTD, AHS & EE)

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5
Q

epizootiology of Orthoreovirus in birds

A
  • mainly chicken & turkeys
  • in young birds
  • resistance above 10 wks of age
  • V resistant
  • inf PO
  • shed by faeces
  • Germinative inf
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6
Q

Orthoreovirus in birds pathogenesis

A
  • PO (trypsin resistant)
  • (trypsin sensitive strains, airborne)
  • propagation in intestinal epithelial cells & bursa of fabricus)
  • epithelial damage
  • viraemia
  • virus dissemination
  • necrotic inf. foci in organs tenosynovitis and arthritis
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7
Q

Orthoreovirus in birds main diseases

A

arhritis-tenosynovitis
enteritis
hydropericardium (in geese)
resp
immunosuppression
CNS signs

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8
Q

Orthoreovirus in birds arthritis & tenosynovitis CS

A
  • 4-8wks broilers, poor keeping
  • lameness
  • swollen tiobio-tarsal, tarso-metatarsal joint
  • rupture of the m.gastrocnemius
  • decreased BW (eco. loss)

(several serotypes)

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9
Q

Orthoreovirus in birds arthritis & tenosynovitis diagnosis

A

RT-PCR
Ab detection: ELISA

exp infection of day old chicks : footpad or IM

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10
Q

Orthoreovirus in birds arthritis & tenosynovitis prevention

A

vaccines: live, attenuated & inactivated
- chickens with yolk immunity : 5-7 wks
- chikens without yolk immunity: 1dy old + vacc against Marek

+ before laying period : inactivated vaccine

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11
Q

Runting stunting syndrome (RSS) in which animals

A

chicken

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12
Q

Poult enteritis and mortality complex syndrome (PEMS) which animals

A

turkey

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13
Q

RSS & PEMS disease

A

enteritis
feather problems (helicopter)
cartilage necrosis
enlarged intestines
inflammation of parenchymal organs

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14
Q

Orthoreoviruses in waterfowl

A

classical & new type (mortality higher in new type)
lethargy
lameness
kindey, liver, spleen enlarged
arthritis

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15
Q

Orthoreoviruses in mammals

A

PO/aerogenic
shed by faeces
mainly in calves (diarrhea, resp)
colostrum Ab protects up to 5 months

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16
Q

Rotavirus genus how many serotypes

A

10 serotypes

17
Q

Rotavirus ST A infects which animals

A

mammals and birds are susceptible, 90% of human cases

18
Q

Rotavirus ST B infects which animals

A

human, pig, cattle, sheep, rat

19
Q

Rotavirus ST C infects which animals

A

pig, rarely human

20
Q

Rotavirus pathogenesis

A

PO/faeces
infection at birth of few days old
propagation in SI
damage epithelial cells
shortened villi
diarrhea
exciccosis

21
Q

Rotavirus infections in domestic animals CS

A
  • mainly 1-2 wko (incubation 1-2dy)
  • massive diarrhea
  • lethargy
  • coinfection
  • in older animals: sever cases due to immunosuppression
22
Q

Rotavirus infections in domestic animals mortality

A

usually low, can increase with coinfections

23
Q

Rotavirus infections in domestic animals patho

A

enlarged intestines
villus atrophy

24
Q

Rotavirus infections in domestic animals Diagnosis

A

virus detection from faeces, mucosa of SI:
- RT-PCR, Elisa

25
Q

Rotavirus infections in domestic animals prevention

A

vaccinate pregnant animals in their third trimester twice with inactivated multivalent vaccines (protection with colostrum)

26
Q

Human rotavirus infections

A

Newborns → 5-year-old children
low income countries
vaccination 2-4 mths with live vaccine, PO

Epi MT (15 decks)

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