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Epi MT > CaliciViruses > Flashcards

CaliciViruses Flashcards

1
Q

Calicivirus genome

A

ssRNA (subgenomic mRNAs)

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2
Q

Calicivirus euryxen or stenoxen

A

stenoxen

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3
Q

Calicivirus antigenicity

A

good

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4
Q

main diseases caused by Calicivirus

A

Vesivirus:
- vesicular exanthema of swine
- feline calicivirus Infection

Lagovirus:
- rabbit haemorrhagic disease
- european brown hare syndrome

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5
Q

Calici virus

norviruse & sapovirus genus

A

food-born human gastroenteritis
no cross protection

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6
Q

Vesicular exanthema of swine history/occurence

A

absent in swine BUT present in seals in pacific coast of America

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7
Q

Vesicular exanthema of swine causative agent

A

Vesivirus genus
seal (natural hosts)/pigs

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8
Q

Vesicular exanthema of swine epizzotiology

A

inf: raw meat
swine shed by saliva, excretes
transmision with raw pork
survives in environment

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9
Q

Vesicular exanthema of swine CS

A

lethargy, vesicles: mouth, snouts, limbs-lameness
lesions heal rapidly
mortality in piglets
seals: skin lesions, abortion

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10
Q

Vesicular exanthema of swine diagnosis

A

not notifiable disease but differentiate from FMD
PCR, ELISA

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11
Q

Vesicular exanthema of swine control & prevention

A

heat treatment of meat (seafood) before feeding to swine

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12
Q

Feline calicivirus infection serotypes

A

only one, but antigenic variants

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13
Q

Feline calicivirus infection epizootiology

A

shed: excreta
transmission by direct contact
long term carriers & continuously shedder cats (persisting inf. in tonsils and nasopharyngeal mucosa)
FIV infection facilitates infection

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14
Q

Feline calicivirus infection pathogenesis

A
  • oronasal
  • pharynx
  • viraemia
  • lungs, mouth, throat, pads, joints (visceral organs, very virulent strains)
  • shedding in saliva, faeces & urine
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15
Q

Feline calicivirus infection CS

A

erosions in oral cavity, margin of tongue, nose, pads (heals in 3 wks)
mild resp & conjunctival signs
lameness (has been observed after vaccination)

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16
Q

Feline calicivirus infection mortality

A

low, but exciccosis, secondary bact inf.

16
Q

Feline calicivirus infection virulent systemic FCV CS

A

severe systemic syndrome
vasculitis, face & pad oedema, resp, icterus
more severe in adults (in vaccinated cats too)

17
Q

Feline calicivirus infection chronic stomatitis CS

A

lymphoplasmatic stomatitis & gingivitis complex

18
Q

Feline calicivirus infection DDx

A

Feline rhinotracheitis
bordetella
chlamydophila

19
Q

Ribavirin is a treatment of Feline calicivirus infection

A

false, in vitro efficient , in vivo toxic

20
Q

how long can maternal antibodies last for against Feline calicivirus infection

A

10-14wks

21
Q

Feline calicivirus infection vaccines

A

attenuated and inactivated vaccines
primary vacc: 9 and 12wks old
vaccine can protect for 1 yr
protects from signs but not infection

22
Q

Rabbit haemorrhagic disease occurence

A

worldwide

23
Q

Rabbit haemorrhagic disease pathogenesis

A

PO, air, conjunctival
viraemia
propagation in liver
vasculitis

24
Q

Rabbit haemorrhagic disease CS

A

liver dystrophy
thrombo-embolia in airways and visceral organs
haemorrhages

25
Q

Rabbit haemorrhagic disease mortality

A

up to 100%

26
Q

Rabbit haemorrhagic disease virus 1

A

resistent in environment
cannot be propagated in cell culture
CS in older animals

mortality 70-90%

27
Q

Rabbit haemorrhagic disease virus 2

A

rabbit and hare
longer incubation
younger rabbit
serologically different to 1

28
Q

Lagovirus europaeus

European brown hare syndrome virus

A

only hare
hepatic necrosis and death

29
Q

European brown hare syndrome CS

A

hyperacute: none, death
acute: foamy/ bloody discharge, mucosal cyanosis
terminal opisthotonus

30
Q

European brown hare syndrome shedding

A

via fecease & excreta- very contageous a few virion is sufficient for infection by conjunctival route

direct transmission

31
Q

Rabbit haemorrhagic disease (European brown hare syndrome ) diagnosis

A

notifiable
high mortality
RT-PCR

32
Q

Rabbit haemorrhagic disease (European brown hare syndrome ) treatment

A

no treatment
vaccination: inactivated vaccine at 4-5wks old, 1x/year

Epi MT (15 decks)

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