Myxomatosis & Fowlpox Virus

Question 1

Myxomatosis in general

Answer 1

wild & domestic rabbits
presence of oedemic swelling or firm tumors on head

(rarely resp symptoms)

Question 2

myxoma meaning in greek

Answer 2

muxa = mucous
oma= tumor
tumour of connective tissue embedded in mucous

Question 3

Myxomatosis occurence

Answer 3

australia, europe, USA, central + south america

Question 4

Myxomatosis causative agent

Answer 4

Myxoam virus

Question 5

Myxoma virus general aspect

Answer 5

• heat sensitive
• in scabs, is infective for months

Question 6

which hosts has the moste severe CS of Myxomatosis

Answer 6

Wild & domestic rabbit

Question 7

Myxomatosis transmission

Answer 7

insects, mosquitoes (for wks)
fleas (in winter for mnths)
direct contact (breeding)

Question 8

Myxomatosis forms

Answer 8

typical/nodular: oedemic tumors predilection sites
atypical/amyxomatous: resp signs

Question 9

Myxomatosis pathogenesis

Answer 9

Vector → skin: primary replication → hydropic degeneration of the epithelial cells,
vesicles filled with serous fluid → skin necrosis
→ viraemia → damage of blood vessels → serous infitration of the corium, tumour-like myxoma cell proliferation and serous infiltration→ moist nodules in the skin

Question 10

Myxomatosis incubation time

Answer 10

7-14 dys

Question 11

Myxomatosis typical form CS

Answer 11

moist nodules on: eye, lips, nose, anus, etc
“lionhead”
blepharoconjunctivitis, rhinitis

100% mortality

Question 12

Myxomatosis CS of Nodular form caused by viral strains with lower virulence

Answer 12

at predilection site but smaller, less moist nodules

(20-90% mortality)

Question 13

Myxomatosis CS of Atypical/amyxomatous form

Answer 13

intensive farms
lower virulence strains
resp signs
very very few skin nodules

(83% mortality)

Question 14

Myxomatosis diag

Answer 14

PCR

Question 15

Myxomatosis vaccine

Answer 15

attenuated, before mosquito season (IM)

Question 16

Fowlpox causative agent

Answer 16

Avian pox viruses

Question 17

Fowlpox general description

Answer 17

lesions on skin & mucosa of domestic & wild birds

Question 18

Fowlpox occurence

Answer 18

worldwide
Pheasant, turkey, pigeon & chicken

Question 19

Fowlpox source of infection

Answer 19

wet rainy weather (pigeon & wild birds)
fall, winter time (chicken & turkey)

Question 20

Fowlpox pathogenesis

Answer 20

Homologous strains:
* 1. per os, inhalation, skin lesion
* 2. primary asymptomatic replication (at the site of entry)
* 3. viraemia
* 4. organs, mucosa, skin (second replication site)
In case of survival:
* 5. secondary viraemia
* 6. replication in the skin (flourishing) Heterologous strains:
* Only primary replication

Question 21

Fowlpox how many types

Answer 21

4
Cutaneous form local
diphteric (wet) malignant
mixed form
acute haemorrhagic form

Question 22

Fowlpox, cutaneous local form

Answer 22

featherless areas
local lesions
animal usually recovers

Question 23

Fowlpox diphteric malignant form

Answer 23

anorexia, coryza, conjunctivitis
Rep tract
membrane: nodule, converge and covered with fibrin-> anorexia wasting
death or recovery

Question 24

Fowlpox mixed form CS

Answer 24

Pocks on the skin & mucosa
death or recovery

Question 25

Fowlpox Acute haemorrhagic form CS

Answer 25

rapid death with no clinical signs

Question 26

Fowlpox chicken CS

Answer 26

mainly diphteric
(imunized birds: resp signs without nodules)

Question 27

Fowlpox turkey CS

Answer 27

diphteroid form, infertile eggs

Question 28

Fowlpox Pheasant CS

Answer 28

resp signs

Question 29

Fowlpox pigeon CS

Answer 29

diphteroid form

Question 30

Fowlpox parrot CS

Answer 30

rare
conjunctivitis, ulcers around eye, necrotic ulcers in nasal cavity

Question 31

Fowlpox vaccination

Answer 31

attenuated fowl/pigeonpox virus
Wing Web vaccination