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Picornaviridae Flashcards

1
Q

Picornavirus vector

A

none

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2
Q

Aphtovirus main disease

A

FMD

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3
Q

Aviheptovirus main disease

A

Duck hepetatitis

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4
Q

Cardiovirus main disease

A

encephalomyocarditis

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5
Q

Enterovirus main disease

A

SVDV

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6
Q

Teschovirus main disease

A

Porcine teschovirus

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7
Q

Tremovirus main disease

A

Avian encephalomyelitis

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8
Q

TESCHOVIRUS ENCEPHALOMYELITIS has also been called

A

Teschen D (higher virulence)
Talfan D (lower virulence)

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9
Q

Teschovirus ST

A

serotype 1: virulence variants
* Teschen: higher virulence
* Talfan: lower virulence
serotypes 2-11:
* milder clinical signs, healing

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10
Q

Teschovirus susceptible species

A

only pigs

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11
Q

Teschen & Talfan disease species differrence

A
  • Teschen disease: clinical signs in all age groups
  • Talfan disease: clinical signs below 4 months (mainly 3-8 weeks), maternal immunity
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12
Q

Teschovirus epidemiology

A

spread in : meat, brain, faeces, swill
shed in faeces for 7-8wks
resistant in environment (indirect inf)

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13
Q

Teschovirus Pathogenesis

A

PO/ nose (CNS)
prim. rep.: lYmphoid tissue of GIT
(asymptomatic, shedding virus)
viraemic phase
neural phase (2nd virus rep)

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14
Q

Teschen Disease CS

A

piglets: ataxia, flaccid paralysis, resp paralysis
adults: flaccid paralysis
some may recover (mvmt disorders)

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15
Q

Talfan Disease CS

A

piglets below 4mths (before weaning)
transient paralysis of hindlimbs
recover, ataxia can remain

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16
Q

Crumbling mouvements is a CS of which disease

A

Teschovirus serotype 2

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17
Q

Teschovirus Patho

A

no gross patho
histo: necrosis, degeneration
- grey matter of the brian (ST2 also white matter)
- ventral horns of the spinal cord

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18
Q

Teschovirus diagnosis

A

RT-PCR

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19
Q

Teschovirus DDx

A

diseases with CNS signs
rabies, CSF, ASF, Aujesky, Glassers

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20
Q

Teschovirus prevention/ control

A

notifiable in HU
not OIE listed since 2005
no vaccines anymore

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21
Q

Swine vesicular Disease causative agent

A

SVD virus, enterovirus genus

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22
Q

Swine vesicular Disease susceptible species

A

only pigs

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23
Q

Swine vesicular Disease resistancy

A

good

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24
Q

Swine vesicular Disease Pathogenesis

A

PO
epitheliotropic virus
rep epithelium of throat and gut
viraemia
vesicles
CNS, heart & faetus (rare)

no mortality

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25
Q

Swine vesicular Disease CS

A

vesicles: nose, oral mucosa, legs, (ruptured within 2dys)
limping
fast recovery

26
Q

Swine vesicular Disease Diagnosis

A

RT-PCR
VN, ELISA (to recognize asymptomatic carriers)

27
Q

Swine vesicular Disease DDx

A

FMD
Vesicular exanthema of swine
Vesicular stomatitis
Vesicular disease caused by Seneca virus A

28
Q

Swine vesicular Disease Prevention/control

A

notifiable D in HU
not WOAH listed
no vaccines

29
Q

Vesicular disease caused by Senecavirus A occurence

A

USA
Chine
Italy
Brazil

30
Q

Vesicular disease caused by Senecavirus A epidemiology

A

infection with discharges (indirect)

31
Q

Vesicular disease caused by Senecavirus A CS

A

piglets below 1 wk (CNS sings)
growers: vesicles on coronary band

adults do not die

32
Q

Avian Encephalomyelitis (epidemic tremor) occurence / atiology

A

clinical form not common (vaccination)
tremovirus
1 ST
highly resistant

33
Q

Avian Encephalomyelitis (epidemic tremor) epidemiology

A

chicken, phaesants (all age)
maternal protection for 3-6wks
CS in 1-3wks old up to 4-5wk old
spread: germinative, faeces (fast spread)

34
Q

Avian Encephalomyelitis (epidemic tremor) lethality

35
Q

Avian Encephalomyelitis (epidemic tremor) pathogenesis

A

PO
rep mucous membrane of gut
viraemia: pancreas, liver, ovarium (does not kill it) CNS
shedding: faeces
good immunity

36
Q

Avian Encephalomyelitis (epidemic tremor) CS

A

nervous signs: tremor, ataxia, paralysis
older animals: subclinical, egg prod drops by 5-10%

37
Q

Avian Encephalomyelitis (epidemic tremor) patho

A

no gross lesions
histo: CNS, grey matter
degeneration of neurons

38
Q

Avian Encephalomyelitis (epidemic tremor) DDx

A

NDV
avian influenza
Marek
encephalomalacia

39
Q

Avian Encephalomyelitis (epidemic tremor) prevention

A

fresh inf: no hatching for 1 mth
vaccine: live vaccine in drinking water (at least 1mth before laying)

40
Q

Duck viral hepatitis aetiology

A

ST1: now duck hepatitis A
ST2: now astrovirus
ST3: now astrovirus
Duck hepatitis A virus 3 genotypes:
G1: highly pathogenic
G2 & 3: less pathogenic

41
Q

Duck viral hepatitis epidemiology

A

inf: PO, NO germinative
shed in faeces
day old duckling: 90% mortality
2-3wks of age 50% mortality

42
Q

Duck viral hepatitis pathogenesis

A

PO
rep mucous membrane of GIT
viraemia

43
Q

Duck viral hepatitis immunity

A

long lasting, yolk immunity 3-6wks

44
Q

Duck viral hepatitis CS

A

cs seen in young ducklings
peracute: largescale death in a few hours
acute: spasmodical paddling (opisthostonus, hunched back)

45
Q

Duck viral hepatitis prevention

A

inactivated vaccine: layers (booster needed)
attenuated: layers and day old duckling

46
Q

encephalomyocarditis occurence

A

worldwide
clinincal form is rare
zoonotic

47
Q

encephalomyocarditis host

A

wide host range
maintained by rodents (asymptomatic)
swine, elephant, etc

48
Q

encephalomyocarditis mortality

A

new-born: 25-50%
growers, fattening: 5-25%

49
Q

encephalomyocarditis pathogenesis

A

PO
rep in tonsils
viraemia:
- heart, myocarditis
- SI: shedding
- foetus: abortion
- CNS: encephalomyelitis

50
Q

encephalomyocarditis maternal immunity

51
Q

encephalomyocarditis CS

A

piglets (4-5wks): heart failure, ataxia, paralysis
growers: dyspnea, death
sows: repro problems

52
Q

encephalomyocarditis prevention/control

A

inactivated vaccines in some countries
rodent control

53
Q

mamastrovirus disease

A

human, swine, cattle, cat: gastroenteritis

54
Q

Avastrovirus diseases

A

chicken astrovirus: Avian nephritis 1 & 2
duck astrovirus 1 & 2
turkey astrovirus

55
Q

Astrovirus resistancy

A

very resistant

56
Q

Avian nephritis epidemiology

A

only in chickens
any age
mortality 1-10% in the first week
spread by faeces

57
Q

Avian nephritis pathogenesis

A

PO
rep: gut epithelium
viraemia
rep in epithelial c of proximal tubules

58
Q

Avian nephritis CS

A

CS in first 4 wks
day old chickens: diarrhea, kidney lesion
chronic cases: visceral urate deposit & death

59
Q

Avian nephritis patho

A
  • enteritis
  • nephrosis
  • urate deposition in chronic cases
60
Q

Avian nephritis diagnosis & prevention

A

RT-PCR
no vaccines

61
Q

duck hepatitis caused by astrovirus

A

CS & patho
Diag & prevention

just like duck hepatitis caused by Avihepatovirus

62
Q

turkey astrovirus disease

A

2 ST
CS : diarrhea in young

Epi MT (16 decks)

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