Polymyxins Flashcards
1
Q
Polymyxins cover?
A
Gram negative bacteria such as Enterobacter spp, E.Coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa
2
Q
Polymyxins are usually reserved for?
A
Multi-drug resistant gram negative pathogens
3
Q
Colistimethate sodium solution inhalation must be mixed when?
A
Immediately prior to administration
4
Q
Warnings of colistimethate
A
Dose-dependent nephrotoxicity and neurotoxicity
5
Q
Colistimethate sodium is the prodrug of?
A
Colistin
6
Q
Boxed warnings of polymyxin B sulfate
A
Nephrotoxicity and neurotoxicity which can result in respiratory paralysis from neuromuscular blockade
7
Q
1mg = ? units polymyxin B
A
10,000
