Pneumocystis Jiroveci pneumonia Flashcards

1
Q

What type of organism causes
Pneumocystis Jiroveci pneumonia?

A

Fungus

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2
Q

What is the name of the fungus that causes Pneumocystis Jiroveci pneumonia?

A

Pneumocystis jiroveci

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3
Q

What is Pneumocystis jiroveci the most common form of?

A

Opportunistic infection in people with AIDS

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4
Q

Who is most commonly affected by Pneumocystis jiroveci?

A

Individuals with HIV who are noncompliant with their cART regimens or antibiotic prophylaxis.

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5
Q

Who should be given prophylaxis for Pneumocystis jiroveci?

A

All patients with a CD4 count < 200/mm³

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6
Q

How do people with Pneumocystis jiroveci present?

A

Fever
Non productive cough
Exertional breathlessness

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7
Q

What is a common complication of Pneumocystis Jiroveci pneumonia?

A

Pneumothorax

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8
Q

What are some possible extrapulmonary manifestations of Pneumocystis Jiroveci pneumonia?

A

hepatosplenomegaly
lymphadenopathy
choroid lesions

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9
Q

How is Pneumocystis Jiroveci pneumonia diagnosed?

A

Chest x-ray

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10
Q

What might you see on a chest x-ray of someone with Pneumocystis Jiroveci pneumonia?

A

Bilateral interstitial pulmonary infiltrates

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11
Q

How can the chest x-ray appear in 10% of cases?

A

Normal

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12
Q

If the chest x-ray is normal but Pneumocystis Jiroveci pneumonia is suspected, what investigation would you do?

A

CT scan

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13
Q

What would you look for on a CT scan in someone in with pneumocystis jiroveci pneumonia?

A

cysts and nodules.

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14
Q

What else would indicate pneumocystis jiroveci pneumonia?

A

Exercise induced desaturation

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15
Q

What is the gold standard diagnostic test for pneumocystis jiroveci pneumonia?

A

Bronchoscopy with bronchoalveolar lavage

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16
Q

What are bronchoscopy samples stained with to diagnose PJP?

A

Grocott’s silver stain, which shows a characteristic “Mexican hat” appearance.

17
Q

What is the medical management of PJP?

A

Co-trimoxazole

18
Q

What is the medical management in severe cases of PJP?

A

IV pentamidine