Asthma Diagnosis Flashcards

1
Q

What are the main tests for asthma?

A

Fractional exhaled nitric oxide (FeNO)
Spirometry
Peak Flow

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2
Q

Why is NO now being used in the diagnosis of asthma?

A

Inducible (iNOS) levels tend to rise in inflammatory cells, particularly eosinophils
Levels of NO therefore typically correlate with levels of inflammation.

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3
Q

How are patients >= 17 years diagnosed with asthma?

A

all patients should have
–spirometry with a bronchodilator reversibility (BDR) test
– a FeNO test

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4
Q

How are children 5-16 years diagnosed with asthma?

A

Spirometry with a bronchodilator reversibility (BDR) test

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5
Q

When might you consider carrying out an FeNO in a child 5-16?

A

If there is normal spirometry or obstructive spirometry with a negative bronchodilator reversibility (BDR) test

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6
Q

How should a diagnosis of asthma be made in a child younger than 5?

A

On clinical judgement

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7
Q

What is considered a positive FeNO in adults?

A

> = 40 parts per billion (ppb)

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8
Q

What is considered a positive FeNO in children?

A

> = 35 parts per billion (ppb)

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9
Q

What FEV1/FVC spirometry ratio would suggest asthma?

A

FEV1/FVC ratio less than 70%

Obstructive

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10
Q

What is considered a positive reversibility testing score in adults?

A

A improvement in FEV1 of 12% or more and increase in volume of 200 ml or more

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11
Q

What is considered a positive reversibility testing score in children?

A

An improvement in FEV1 of 12% or more

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