PLASMA RICH PLASMA

Question 1

how are platelet rich plasma used in acute bony injury?

Answer 1

from the bloodstream

Question 2

release of inflammatory factors like what?? are essential for coordinating the bone healing cascade

Answer 2

PDGF
TGF-I
IGF
VEGF

Question 3

when blood is centrifuged what are the three components?

Answer 3

platelet rich plasma
platelet poor plasma
RBCs

Question 4

what are the indications for soft tissue healing in the operating room?

Answer 4

achilles tendinosis
chronic microtrauma
fibro fatty infiltration
large tendon resection
goal:end to end healing at host graft interference

goal:end to end healing at host/graft interface

Question 5

what are the indications of plasma rich plasma for soft tissue healing?

Answer 5

chronic microtrauma
fibrofatty infiltration
tendinosis
plantar faciosis
PRP injection at site

goal:replacement of degenerative tissue with collagen fibers

Question 6

mesenchymal stem cells used for?

Answer 6

orthofix
cancellous allograft
allogenic MSCs
osteogenesis

Question 7

indications for use in high risk bone healing?

Answer 7

fusions/osteotomies/fx
tumor defect
non-unions

Question 8

why concentrate the BMA?

Answer 8

RBCs out compete the MSCs for oxygen