CONNECTIVE TISSUE HEALING Flashcards
what are the examples of CT?
tendons, ligaments, joint capsule, muscle
CT healing phases?
lag(substrate), 0-14 days
fibroproliferative, 14-21 days
maturation, 4th week to 2 yrs
skin heals faster than CT, T/F?
true
when does the reparative phase start?
3-4 weeks
cartilage healing has limited reparative potential, T/F?
T, poor blood supply and lack of undifferentiated cells
T/F, the ankle has more populated cells?
T
for bone healing, bone composition consists of what cells?
osteocytes
osteoblasts
osteoclasts
-remember howships lacunae
primary bone healing has callus or no callus?
secondary bone healing?
remodels according to what law?
no callus
callus
-wolffs law
primary bone healing contains the cutting cone, what parts have osteoblasts and osteoclasts?
TAIL has osteoblast
TIP has osteoclast
what are the phases of fracture healing?
inflammation
repair
remodeling
major issues with bone healing?
delayed union non union -atrophic -hypertrophic pseudoarthrosis hypertrophic bone formation local factors systemic factors -malnutrition -smoking -DM -anti-inflammatory meds
in the issues with bone healing, especially non-union, what is the effect specifically for atrophic and hypertrophic?
lack of blood flow, surgery
lots of bone callus, sides of bone don’t meet due to lack of immobilization
name this systemic factor in the issue with bone healing?
reduces activity and proliferation of osteochondral cells
decreased callus formation
malnutrition
name this systemic factor in the issue with bone healing?
inhibits osteoblasts
nicotine causes vasoconstriction diminishing blood flow at fracture site
smoking
name this systemic factor in the issue with bone healing?
associated with collagen defects including decreased collagen content, defective cross linking and alterations in collagen type ratios
DM
