Pityriasis Lichenoides

Question 1

Pityriasis Lichenoides et Varioliformes Acute and Pityriasis Lichenoides Chronica

Answer 1

acute and chronic forms of the disease, a papular clonal T-cell disorder

Question 2

Epidemiology

Answer 2

Mainly male, prevalent in young adults

Question 3

Pathogenesis

Answer 3

Unknown, may be due to a foreign antigen or after vaccines

Question 4

Clinical lesions

Answer 4

recurrent crops of erythematous purpuric papules. PLEVA: acute, PLC: chronic

Question 5

PLEVA

Answer 5

ulcers, crusts, vesicles, papules. Often resolve within weeks but may last 2-4 years. a/w fever, malaise, arthritis.

Question 6

Severe form of PLEVA

Answer 6

Febrile ulceronectrotic Mucha Habermann disease (FUMHD) involving the mucosa, GI tract and pulmonary systems

Question 7

PLC

Answer 7

erythematous brown papules with scale, can leave hypopigment when they recede. can either spontaneously resolve or be chronic and relapsing

Question 8

PLC with diffuse distribution will last

Answer 8

11 months

Question 9

PLC with peripher distrubution will last

Answer 9

several years

Question 10

Tx

Answer 10

stop the offending drug, topical steroids, doxycycline, erythromycin (oral abx for antiinfamm properties x months then tapered), phototherapy, antihistamines

Question 11

Tx of choice for children

Answer 11

Erythromycin

Question 12

Tx for unresponsive cases

Answer 12

MTX, cyclosporine, systemic steroids