Grover's Disease Flashcards

1
Q

Epidemiology

A

more prevalent in caucasian men with significant photo damage > 40 years of age. Peaks in winter and the summer

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2
Q

Triggers for Grovers Disease

A

heat, sweat, friction, UV radiation

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3
Q

Pt with this condition are more likely to have Grovers Disease

A

asteatotic eczema

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4
Q

Clinical features

A

pruritic or asymptomatic papules, vesicles, photodistribution on chest, back, and thighs

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5
Q

Dermatopathology

A

acantholysis (loss of the dermasomes that hold keratinocytes together)

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6
Q

ddx

A

darier and hailey hailey disease are seen in younger individuals and have a family hx. PF will be seen via direct immunoflorescence, Grovers would not be remarkable

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7
Q

Treatment

A

control itch, avoid sweating and heat, topical corticosteroids/antipruritics, vit D analogues

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8
Q

Systemic adverse effects of systemic corticosteroids

A

Growth retardation, hypothalamopituitary adrenal axis suppression, Cushings

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9
Q

S/e topical steroids

A

atrophy, striae, hypopigment

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10
Q

Elidel and Protopic

A

decrease pruritus by blocking Tcells and cytokines. Good for steroid sparing areas. Can have transient skin irritation

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11
Q

Calcipotriene adverse effects

A

hypercalcemia, irritation, photosensitivity, allergic contact derm

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12
Q

Isotretinoin patho

A

decreases inflammation and the size of the pilosebaceous duct. Isotretinoin sometimes used for persistent grovers

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