Pierre-Robin Sequence

Question 1

What is Pierre robin sequence?

Answer 1

Set of abnormalities affecting the head an face consisting of: -micrognathia -glossoptosis (tongue that is placed further back than normal) -airway obstruction -cleft lip

Question 2

Syndromic Pierre robin includes:

Answer 2

• Stickler syndrome (visual and hearing impairment with spine abnormality)
• Campomelic dysplasia

Question 3

What are phenotypic features of Pierre robin sequence?

Answer 3

-Difficulty breathing and eating leading to failure to thrive -Micrognathia -Glossoptosis (tongue displaced towards the back of mouth) +/- cleft lip