Physiology Of Pain Flashcards

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1
Q

What is procaine?

A

A local anesthetic which black sodium channels from working (NA blocker)

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2
Q

What is a TRP channel?

A

Transcient Receptor Potential Channels: Respond to strong stimuli which transmit pain.

Ex. Chili pepper sensation

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3
Q

Where are the cell bodies of 1st order sensory neurons? What is the grouping of the cell bodies called?

A

Outside the spinal cord; Dorsal root ganglia

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4
Q

What part of the brain modulators pain information sent from the sensiry cortex/hypothalamus?

A

Periaqueductal grey matter

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5
Q

What are the three classes of endogenous opioids?

A
  1. Enkephalins
  2. Endorphins
  3. Dynorphins
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6
Q

What is gate control theory?

A

Discomfort stimulus from skin travel along sensory neuron to dorsal horn, synapsids with motor neurons, travels along spinal nerve to skeletal muscle causing withdrawal from pain stimulus.

Ex. Rubbing hand after a cut stimulates receptors of innocuous stimuli

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7
Q

What is Parasthesias?

A

Numbness or tingling

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8
Q

What is dyestesias?

A

Electric shock phenomenon

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9
Q

Hyperesthesia

A

Increased sensitivity to mild painful stimuli

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10
Q

Hyperalgesia

A

Increased sensitivity to normally painful stimuli

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11
Q

Hyperpathia

A

Pain produced by normally non painful stimuli

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12
Q

Define phantom pain

A

Pain perceived to arise from a part of body that has been amputated

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13
Q

How does somatic pain differ from visceral pain?

A

Somatic:

  • Sharp
  • A-delta fibers
  • Localized

Generalized:

  • Generalized
  • Ache, pressure
  • C Fiber type
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