Physiology Flashcards
“The study of nature;” Deals with the normal functioning of living organisms and their parts
Physiology
The mechanism, explained in terms of physiology, by which a disease process causes the body to fail.
Pathophysiology
This governs the basic acitivities of cell and coordinates multiple-cell actions
Signalling
An entity that codes or conveys information
A signal
A tailor-made clinical model whereby therapy is delivered on an individualised basis
Personalised medicine
Gene therapy for Cystic Fibrosis, and drug recommendations based on molecular subtyping of cancer are examples of what type of medicine?
Personalised medicine
The grouping of patients based on risk of disease or response to therapy by using diagnostic tests or techniques
Stratified medicine
Applying basic research to a clinical setting
Translational research
A characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention
Biomarker
Name an example of a biomarker
BRCA1 or HER2 (Breast cancer protein biomarkers)
The regulation of the state of cells and of the body. Normally about maintaining something at a particular desired level or set point.
Homeostasis
The regulatory mechanism present in many biologicical reactions that allows certain pathways to be turned on or off
Feedback
A type of regulation in which the end product of a process in turn reduces the stimulus of that same process
Negative feedback
Temperature regulation is an example of what type of feedback?
Negative feedback
Blood glucose control is an example of what type of feedback?
Negative feedback
The process by which the end products of an action causes more of that action to occur in a feedback loop, which ultimately amplifies the original action.
Positive feedback
Contractions of labour are an example of what type of feedback?
Positive feedback