MSI Immunodeficiency diseases Flashcards

1
Q

How many forms of Primary Immunodeficiency disorders have been discovered to date?

A

> 300

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2
Q

In healthy infants there is normally a period of relative antibody deficiency around ___ months known as ‘transient hypogammaglobulinemia of infancy; this is a physiological state but can be correlated with increased infections

A

6

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3
Q

Infants with antibody deficiency usually present after _____ months; up until this time they are protected by maternal IgG antibody

A

3-6

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4
Q

A state in which the immune system’s ability to fight infectious disease and cancers is compromised or completely absent

A

immunodeficiency

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5
Q

People with immunodeficiency are more susceptible to infections that are ___________, unusual, severe, protracted, not as responsive to standard therapy, and frequent

A

opportunistic

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6
Q

Key features of immunodeficiency are that there are
components of the immune response system are absent or non functional; Inability to fight infectious diseases and __________.

A

cancers

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7
Q

** _________ deficiencies in general are more susceptible to bacterial infections, such as Neisseria meningitidis

A

Complement

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8
Q

Antibody-deficiency (or humoral immunodeficiency) creates more susceptibility to ___________ bacterial infections such as Streptococcus pneumonia

A

encapsulated

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9
Q

In cellular immunodeficiency patients are more susceptible to _______, fungal, and mycobacterial infections (eg Herpes Simplex virus)

A

viral

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