MSI Immunodeficiency diseases Flashcards
How many forms of Primary Immunodeficiency disorders have been discovered to date?
> 300
In healthy infants there is normally a period of relative antibody deficiency around ___ months known as ‘transient hypogammaglobulinemia of infancy; this is a physiological state but can be correlated with increased infections
6
Infants with antibody deficiency usually present after _____ months; up until this time they are protected by maternal IgG antibody
3-6
A state in which the immune system’s ability to fight infectious disease and cancers is compromised or completely absent
immunodeficiency
People with immunodeficiency are more susceptible to infections that are ___________, unusual, severe, protracted, not as responsive to standard therapy, and frequent
opportunistic
Key features of immunodeficiency are that there are
components of the immune response system are absent or non functional; Inability to fight infectious diseases and __________.
cancers
** _________ deficiencies in general are more susceptible to bacterial infections, such as Neisseria meningitidis
Complement
Antibody-deficiency (or humoral immunodeficiency) creates more susceptibility to ___________ bacterial infections such as Streptococcus pneumonia
encapsulated
In cellular immunodeficiency patients are more susceptible to _______, fungal, and mycobacterial infections (eg Herpes Simplex virus)
viral