Micro and Macro nutrient digestion Flashcards
what are the three products that result from a-amylase breaking down the a 1-4 glycosidic bonds in starch?
- maltose
- maltotriose
- alpha-dextrins
Is starch digested in the stomach?
No, salivary amylase is inactivated in acidic environments. Starch digestion begins in the mouth, paused in the stomach, and then is further digested in the small intestine.
what are the two areas of the digestive tract that produce/secrete alpha amylase?
salivary glands and pancreas (the latter is secreted into the small intestine)
What are the two enzymes that can break down a 1-4 glycosidic bonds?
sucrase and alpha amylase
How are glucose molecules moved from the intestinal lumen into the enterocytes of the small intestine?
They are absorbed via the sodium-glucose transporter on the apical surface of the enterocytes (2 Na along with every 1 Glu)
Excess glucose can be stored within the liver as _________
glycogen
Once glucose is inside an enterocyte, what kind of transporter moves the glucose through the basolateral membrane and on into the bloodstream?
GLUT-2 transporter
Lipase enzymes hydrolyse triglycerides into what two component parts?
Fatty acids and di-glycerides
In the process of fat digestion, where do micelles go (within the enterocyte) to assist with the synthesis of triglycerides?
the endoplasmic reticulum and Golgi apparatus
Lipids enter the enterocyte as _______ and exit the basolateral aspect of the cell into the lymphatic system as __________
Micelles, chylomicrons
__________ are the lymphatic vessels of the small intestine (found inside each villus) that aid with the absorption of fat
Lacteals
What type of movement/contraction in the stomach helps to break up fat globules into smaller droplets?
Segmentation
what converts pepsinogen into its active form of pepsin?
The presence of acid in the stomach (HCl released by parietal cells leads to low pH)
Name the two primary pancreatic proteases
Trypsin and chymotrypsin
The pro-enzymes trypsinogen and chymotrypsinogen are activated by which enzyme?
Enterokinase- secreted by the mucosal membrane (brush border) of the duodenum