Physiology 5 (easy) Flashcards
Effect of atrial natriuretic hormone on Na+ reabsorption
Decreases Na+ reabsorption
Effect of PTH on calcium and phosphate reabsorption
Increases calcium reabsorption
Decreases phosphate reabsorption
NaCl reabsorption occurs in which part of the distal tubule?
Early (Na+K+2Cl- transport)
Ca2+ reabsorption
H+ secretion
Na+ reabsorption
K+ reabsorption
(+ aldosterone: K+ secretion when K+ secretory cells are activated)
occurs in which part of the distal tubule?
Late part
early part of collecting duct also very similar to this
(late part of collecting duct permeable to water)
What is the late collecting duct permeable to?
- low ion permeability
- permeability to water (and urea) influenced by ADH
Plasma half life of ADH
10-15 mins
How does ADH work in the collecting duct?
Increases permeability of luminal membrane by inserting new water channels (aquaporins)
Effect of high ADH on permeability
=high water permeability
= hypertonic urine (up to 1400 mosmol/l)
Effect of low ADH on permeability
= low water permeability
= hypotonic urine (
Effect of low ADH on permeability
= low water permeability
= hypotonic urine (
Na+ and water coupling
Proximal tubule and descending lop of henle
Na + and Cl- coupling
Ascending loop of henle and distal tubule
These produce net fluid reabsorption
Proximal tubule and descending loop of henle
These produce dilution of urine
Ascending loop of Henle and distal tubule
Site of hormone action (ADH, aldosterone, atrial natriuretic peptide)
Distal tubule/collecting duct
