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NPTE - MSK > Pharmacology p. 132 > Flashcards

Pharmacology p. 132 Flashcards

1
Q

What drug slows or halts the progression of rheumatic disease? When are they used?

A

Disease-modifying Antirheumatic Agents (DMARDS)

-Used early in disease process to slow progression

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2
Q

What are the implications for the PT of using DMARDS?

A

therapists should recognize that many agents have high levels of incidence toxicity

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3
Q

What drug provides hormonal, anti-inflammatory, and metabolic effects including suppression of articular and systemic diseases? they can also reduce inflammation in chronic conditions that can cause damage to healthy tissues

A

Glucocorticoid Agents (corticosteroids)

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4
Q

What are implications for the PT of a pt using Glucocorticoid agents (corticosteroids)? (4)

A
  1. PT must wear a mask due weakend immune system
  2. must be aware of signs of toxicity (moon face, buffalo hump, and personality changes)
  3. Risk for osteoporosis and muscle wasting
  4. Care for injected joints due to increased tendon laxity or weakening
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5
Q

What drug provides analgesia and pain relief, anti-inflammatory effects, and initiate anti-pyretic (reduces fever)?

A

Nonopoid agents

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6
Q

What are the implications for a PT of pt using Nonopoid agents? (2)

A
  1. can mask pain that allows for movement beyond limitation or false understanding of their level of mobility
  2. Stomach pain needs to be referred to doctor
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7
Q

What drugs provides analgesia for acute severe pain management?

A

Opioid Agents (Narcotics)

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8
Q

What are the implications for the PT of a pt taking Opioid Agents (narcotics)? (2)

A
  1. monitor for side effects, especially respiratory depression
  2. Therapy 2 hours after administration of drug to maximize benefit
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9
Q

RED FLAG: what is the Opioid Overdose Triad?

A
  1. Pinpoint pupils
  2. respiratory depression
  3. unconsciousness
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10
Q

What drug acts on the central nervous system to reduce skeletal muscle tone by depressing internuncial neurons of the brain stem and spinal cord?

A

Muscle Relaxants

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11
Q

What are side effects of muscle relaxants?

A

drowsiness, lethargy, ataxia, and decreased alertness (basically a CNS depressant)

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12
Q

What is the most commonly prescribed medication for pain relief in MSK dysfunction?

A

NSAIDS

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13
Q

Rheumatrex (methotrexate) is a ?

A

DMARD

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14
Q

Arava (leflunomide) is a?

A

DMARD

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15
Q

Roxanol (morphine) is a?

A

Opioid

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16
Q

Demerol (mepridine) is a ?

A

Opioid

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17
Q

OxyCotin (oxycodone) is a ?

A

Opioid

18
Q

Sublimaze (fetanyl) is a ?

A

Opoid

19
Q

Paveral (codeine) is a ?

A

Opioid

20
Q

Aralen (chlorquine) is a?

A

DMARD

21
Q

Plaquenil (hydroxychloroquine) is a ?

A

DMARD

22
Q

Ridaura (auranofin) is a ?

A

DMARD

23
Q

Solganal (aurothioglucose) is a ?

A

DMARD

24
Q

Humira (adalimumab) is a ?

A

DMARD

25
Q

Enbrel (etanercept) is a ?

A

DMARD

26
Q

Dermacort (hydrocortison or cortisol) is a?

A

Glucocorticoid Agent

27
Q

Cordrol (prednisone) is a ?

A

Glucocorticoid Agent

28
Q

Pediapred (prednisolone) is a?

A

Glucocorticoid Agent

29
Q

Medrol (methylprednisolone) is a ?

A

Glucocorticoid Agent

30
Q

Decadrol (dexamethasone) is a ?

A

Glucocorticoid Agent

31
Q

Nasonex (mometasone) is a ?

A

Glucocorticoid Agent

32
Q

Tylenol (acetaminophen) is a ?

A

Nonopoid agent

33
Q

NSAIDS are a ?

A

Nonopoid agent

34
Q

Aspirin (acetlsalicylic acid) is a ?

A

Nonopoid agent

NSAID

35
Q

Aleve (naproxen) is a ?

A

Nonopioid agent

NSAID

36
Q

Celebrex (celecoxib) is a ?

A

Nonopioid agent

NSAID

37
Q

2 side effects of DMARDS?

A

toxicity, liver dysfunction

38
Q

2 side effects of Glucocorticoid Agents (Corticosteroids)?

A

muscle atrophy, drug induced Cushing syndrome

39
Q

2 side effects of non-opoid agents?

A

vertigo, GI distress or bleeding

40
Q

2 side effects of opoid agents (narcotics)?

A

sedation, orthostatic hypotension, constipation

NPTE - MSK (39 decks)

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