Pharmacology p. 132 Flashcards
What drug slows or halts the progression of rheumatic disease? When are they used?
Disease-modifying Antirheumatic Agents (DMARDS)
-Used early in disease process to slow progression
What are the implications for the PT of using DMARDS?
therapists should recognize that many agents have high levels of incidence toxicity
What drug provides hormonal, anti-inflammatory, and metabolic effects including suppression of articular and systemic diseases? they can also reduce inflammation in chronic conditions that can cause damage to healthy tissues
Glucocorticoid Agents (corticosteroids)
What are implications for the PT of a pt using Glucocorticoid agents (corticosteroids)? (4)
- PT must wear a mask due weakend immune system
- must be aware of signs of toxicity (moon face, buffalo hump, and personality changes)
- Risk for osteoporosis and muscle wasting
- Care for injected joints due to increased tendon laxity or weakening
What drug provides analgesia and pain relief, anti-inflammatory effects, and initiate anti-pyretic (reduces fever)?
Nonopoid agents
What are the implications for a PT of pt using Nonopoid agents? (2)
- can mask pain that allows for movement beyond limitation or false understanding of their level of mobility
- Stomach pain needs to be referred to doctor
What drugs provides analgesia for acute severe pain management?
Opioid Agents (Narcotics)
What are the implications for the PT of a pt taking Opioid Agents (narcotics)? (2)
- monitor for side effects, especially respiratory depression
- Therapy 2 hours after administration of drug to maximize benefit
RED FLAG: what is the Opioid Overdose Triad?
- Pinpoint pupils
- respiratory depression
- unconsciousness
What drug acts on the central nervous system to reduce skeletal muscle tone by depressing internuncial neurons of the brain stem and spinal cord?
Muscle Relaxants
What are side effects of muscle relaxants?
drowsiness, lethargy, ataxia, and decreased alertness (basically a CNS depressant)
What is the most commonly prescribed medication for pain relief in MSK dysfunction?
NSAIDS
Rheumatrex (methotrexate) is a ?
DMARD
Arava (leflunomide) is a?
DMARD
Roxanol (morphine) is a?
Opioid
Demerol (mepridine) is a ?
Opioid
OxyCotin (oxycodone) is a ?
Opioid
Sublimaze (fetanyl) is a ?
Opoid
Paveral (codeine) is a ?
Opioid
Aralen (chlorquine) is a?
DMARD
Plaquenil (hydroxychloroquine) is a ?
DMARD
Ridaura (auranofin) is a ?
DMARD
Solganal (aurothioglucose) is a ?
DMARD
Humira (adalimumab) is a ?
DMARD
