pharmacology

Question 1

calculate concentration of drug

Answer 1

dose / volume of distribution

Question 2

what things do cephalosporins and quinolones affect the bioavailability of?

Answer 2

calcium, mag, iron, aluminum

Question 3

what foods should isotretinoin and griseofulvin be taken with

Answer 3

fatty foods (lipophilic)

Question 4

how many half lives does it take for drug to reach steady state (if admin at constant intervals)

Answer 4

~5 half lives

Question 5

which medications are chelated by dairy products

Answer 5

tetracycline, doxycycline, ciprofloxacin

Question 6

what happens when antacids and iron are taken together

Answer 6

binds iron, increased elimination in GI tract

Question 7

examples of drugs that inhibit hepatic metabolism of drugs

Answer 7

erythro
cipro
omeprazole

Question 8

examples of drugs that induce hepatic metabolism of drugs

Answer 8

rifampin
phenobarb
carbamazepine
phenytoin

Question 9

electrolytes wasted with lasix

Answer 9

K, H, Ca

Question 10

electrolytes wasted with thiazides

Answer 10

Na, Cl

–> contraction alkalosis