Pharmacology Flashcards
Define Pharmacodynamics
The mechanism of action of a drug in the body
Define Pharmacokinetics
The mechanism by which the drug moves around the body and is broken down and excreted
What are the 2 types of acetylcholine receptor?
Nicotinic and Muscarinic
What type of muscles does each AC receptor target?
NIcotinic = Voluntary muscle Muscarinic = Smooth muscle
Nicotinic AC repectors are what kind of receptor?
Ion channel receptors
Muscarinic AC receptors are what kind of receptor?
GPCRs
Which ions travel through Nicotinic AC receptors?
Na+, Ca2+, K+
What antagonises Nicotinic receptors?
Tubocuarine and Atracurium
What antagonises Muscarinic receptors?
Atropine
Statins prevent the formation of which molecule? and How?
Cholesterol by binding to the enzyme responsible for its synthesis