Intro to Metabolism

Question 1

What is produced during Glycolysis?

Answer 1

2 pyruvate, 4 ATP (2 net), 2 NADH (per 1 glucose)

Question 2

What is produced in Kreb’s cycle?

Answer 2

4CO2, 6 NADH, 2 FADH2, 2 ATP (per 1 glucose)

Question 3

What happens in oxidative phosphorylation?

Answer 3

Electrons and H+ ions pass between transmembrane complexes and generate the formatiion of ATP and H2O

Question 4

What are the intermediates of Kreb’s cycle?

Answer 4

Acetly-CoA - Citrate (6C) - Isocitrate (6C) - a-ketoglutarate (5C) - Succinyl-CoA(4C) - Succinate (4C) - Fumarate (4C) - Malate (4C) - Oxaloacetate (4C) - Citrate (6C)

Question 5

How are fat metabolised?

Answer 5

Fatty acids (in liver) - Acyl CoA - Acyl Carnitine (translocates to liver mitochondrion) - Acyl CoA - b-oxidation - Acetyl CoA (krebs) - Ketone Bodies - Blood

Question 6

Why are fats better sources of energy than glucose?

Answer 6

They generate 8 acetyl CoA molecules per fatty acid broken down = 131 ATP