Nervous system Flashcards
What are the 2 sections of the nervous system?
Central - Spine/brain
Peripheral - everywhere else
What are the subdivisions of the peripheral nervous system?
Somatic - voluntary controllers
Autonomic - involuntary controllers
What are the 2 subdivisions of the autonomic nervous system?
Sympathetic - Fight or flight
Parasympathetic - Rest and digest
What are the main features of neurones?
Dendrites - bring signals to cell body
Axon - Action potential travels down
Axon terminals - release neuronal commmunicators for dendritic receptor recognition
What is the resting membrane potential across a neurone?
-60mV
What happens during an action potential?
Rapid influx of Na+ ions to +30mV internal membrane potential followed by rapid efflux of K+ ions to return the membrane potential to normal
What are the 4 states of a voltage-gated Na+ channel?
Resting
Open
Inactivated
Closed and inactivated
What does tetrodotoxin (TTX) do?
Paralyses the body
What happens when the action potential reaches the axon terminal?
Release of neurotransmitters across the synapse
What is the relationship between speed of transmission and diameter of axon?
Bigger diameter = faster transmission
What does myelination do?
Increases the speed of conductance by introducing nodes (of ranvier) where the action potential can jump between
What diseases are caused by the loss of myelination?
CNS - MS
PNS - Guillain-Barre
What are the 3 types of Glial cell and their functions?
Microglia - Remove debris
Astrocytes - Regulate the extracellular chemical content
Oligodendrocytes - Provide myelination of axons
What are the 3 types of neurone?
Sensory - carry information to the CNS
Interneurones - carry commands within CNS for complex processing
Motor - cyy information from CNS to effector tissue
What are the 4 main lobes of the brain?
Frontal lobe - cognition/motor control
Parietal lobe - Sensory
Temporal lobe - Auditory/memory
Occipital lobe - vision