Clinical Biochemistry of Ischaemia Flashcards

1
Q

What happens to the blood if there is a build-up of lactate?

A

Blood pH lowers

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2
Q

What happens when ATP production is reduced?

A

Na/K channel is disrupted
Membrane permeability increases
ROS increases
Cell death in 15-20 mins

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3
Q

Which vitamins are the antioxidants?

A

A, C and E

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4
Q

Which enzymes are increased in the blood after cardiac muscle damage?

A
Cardiac troponin-T
Creatine kinase (MB isoform)
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5
Q

Which enzymes are increased in the blood after liver damage?

A
Alanine transaminase (ALT)
Aspartate transaminase (AST)
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6
Q

Which enzymes are increased in the blood after Striated muscle damage?

A

Creatine kinase (MM isoform)

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7
Q

Which enzymes are increased in the blood after exocrine pancreas damage?

A

Amylase

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