Clinical Biochemistry of Ischaemia Flashcards
1
Q
What happens to the blood if there is a build-up of lactate?
A
Blood pH lowers
2
Q
What happens when ATP production is reduced?
A
Na/K channel is disrupted
Membrane permeability increases
ROS increases
Cell death in 15-20 mins
3
Q
Which vitamins are the antioxidants?
A
A, C and E
4
Q
Which enzymes are increased in the blood after cardiac muscle damage?
A
Cardiac troponin-T Creatine kinase (MB isoform)
5
Q
Which enzymes are increased in the blood after liver damage?
A
Alanine transaminase (ALT) Aspartate transaminase (AST)
6
Q
Which enzymes are increased in the blood after Striated muscle damage?
A
Creatine kinase (MM isoform)
7
Q
Which enzymes are increased in the blood after exocrine pancreas damage?
A
Amylase