Pharm1E1 Receptors Flashcards
myenteric plexus- increases smooth muscle tone & contractility
M1
decreases everything in heart
M2
PNS autoreceptor
M2
SNS heteroreceptor
M2
contracts ciliary m. for near vision (lens)
M3
miosis
M3
increases aqueous outflow
M3
endothelium relaxes/vasodilation (by release of NO- only via circulating cholinergic agonists)
M3
bronchoconstriction
M3
bronchial gland stimulation
M3
peristalsis
M3
smooth m. sphincter relaxation
M3
increase GI secretion
M3
bladder wall contraction
M3
GU sphincter relaxation
M3
erection (NO release)
M3
increased acini secretion
M3
PNS - no effect (9)
ectopic pacemakers blood vessels s.m. vessels skin- pilomotor smooth m. eccrine/thermoregulatory sweat glands apocrine/stress sweat glands liver glycogenolysis and gluconeogenesis fat cells kidney
PNS- variable effects on ?
uterus
midriasis- radial m.
alpha 1
contracts blood vessels- skin, splanchnic, skeletal muscle (little effect)
alpha 1
decreases bronchial gland secretion
alpha 1
contracts GI smooth m. sphincters
alpha 1
GU smooth m. walls contract
alpha 1
uterus contracts (when pregnant)
alpha 1
ejaculation
alpha 1
pilomotor smooth m. contracts
alpha 1
apocrine sweat glands (stress)
alpha 1
liver glycogenolysis & gluconeogenesis
alpha 1
decreased aqueous humor production
alpha 2
relaxation of GI smooth m. walls
alpha 2
inhibition of GI secretion
alpha 2
decreased islet B cell secretion
alpha 2
SNS autoreceptor
alpha 2
PNS heteroreceptor
alpha 2
increase all heart actions
beta 1
increased renin secretion
beta 1
relaxes ciliary muscle for far vision (lens)
beta 2
increase aqueous humor production & IOP
beta 2
skeletal muscle relaxes
beta 2
bronchodilation
beta 2
increased secretion- bronchial glands
beta 2
smooth m. walls relax (2)
beta 2 (and alpha 2)
bladder wall relaxation
beta 2
liver gluconeogenesis & glycogenolysis
beta 2 (and alpha 1)
increased secretion of islet B cell
beta 2
lipolysis
beta 3
increased outflow of aqueous humor
alpha & beta
skeletal m. dilation by sympathetic cholinergic fibers
M?
SNS no effect? (2)
endothelium
myenteric plexus
eccrine/thermoregulatory sweat glands
M3 (SNS)
dilation of renal blood vessels
D1
decreased acini secretion
alpha