pharm pt 1 - Sheet1 Flashcards

1
Q

What is a drug?

A

Any chemical that can affect living processes.

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2
Q

What is pharmacology?

A

The study of drugs and their interactions with living systems.

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3
Q

What is clinical pharmacology?

A

The study of drugs in humans.

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4
Q

What is therapeutics (pharmacotherapeutics)?

A

The use of drugs to diagnose, prevent, or treat disease, or to prevent pregnancy.

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5
Q

What are the top 3 characteristics of the ideal drug?

A

Effective, safe, and selective.

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6
Q

What does “selective” mean in terms of drug characteristics?

A

A drug only elicits the response for which it is given (e.g., BP meds).

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7
Q

Why is reversibility important in drug characteristics?

A

If given by mistake, the effects can be reversed.

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8
Q

What makes a drug predictable?

A

Knowing exactly what it will do.

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9
Q

Why is ease of administration important?

A

Simplifies use, often oral and infrequent doses are preferred.

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10
Q

How should an ideal drug interact with other medications or food?

A

It should have no interactions.

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11
Q

What are other characteristics of an ideal drug?

A

Low cost, chemical stability, simple generic name, rapid predictable response, and quick elimination.

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12
Q

What factors affect the intensity of drug responses?

A

Administration, pharmacokinetics, pharmacodynamics, and individual variations.

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13
Q

What are the four components of pharmacokinetics?

A

Absorption, distribution, metabolism, and excretion.

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14
Q

What is pharmacodynamics?

A

The impact of the drug on the body.

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15
Q

What are examples of individual variations that affect drug responses?

A

Physiologic (age, weight, BSA), pathologic (kidney, liver issues), genetics, diet, and tolerance.

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16
Q

What is pharmacogenomics?

A

The study of how genetics influence drug responses.

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17
Q

How does starvation affect drug responses?

A

Lack of protein for binding reduces drug transport in the body.

18
Q

What are the types of tolerance?

A

Pharmacodynamic, metabolic, and tachyphylaxis.

19
Q

What is the placebo effect?

A

A response to a treatment that is not due to its therapeutic effect but the patient’s belief in the treatment.

20
Q

What are the Five Rights of Drug Administration (PMART)?

A

Right patient, drug (med), dose (amount), route, and time.

21
Q

What additional rights do nurses need to ensure?

A

Right assessment, documentation, evaluation, patient education, and patient refusal.

22
Q

Why is understanding pharmacology critical in nursing practice?

A

To prevent med errors, understand drug interactions, and administer drugs safely and effectively.

23
Q

What are the steps in patient care application of pharmacology?

A

Preadministration assessment, dosage and administration, promoting therapeutic effects, minimizing adverse effects, and managing toxicity.

24
Q

What patient education topics are critical for medication?

A

Drug name/category, dosage, schedule, route, expected response, treatment duration, storage, adverse effects, and interactions.

25
Q

What are the steps of the nursing process in drug therapy?

A

Assess, analyze, plan, implement, and evaluate.

26
Q

What are the steps of clinical judgment in drug therapy?

A

Recognize cues, analyze cues, prioritize hypotheses, plan, implement (give the drug), and evaluate.

27
Q

What is included in evaluation during the clinical judgment process?

A

How the drug works, baseline data, and effectiveness.

28
Q

What are the phases of the drug approval process?

A

Preclinical testing (1-5 years), clinical testing (2-10 years, Phases I-III), and postmarketing surveillance (Phase IV).

29
Q

What are drug indications?

A

Conditions for which a drug is approved.

30
Q

Must all prescription drugs have an indication?

A

Yes, all prescription drugs must have some degree of effectiveness and at least one indication.

31
Q

What are unapproved indications called?

A

Unlabeled or off-label uses.

32
Q

What is therapeutic usefulness in drug classification?

A

What is being treated by the drug (e.g., influence blood clotting, lower BP).

33
Q

What is therapeutic classification in drug classification?

A

How the drug acts (e.g., anticoagulants, antihypertensives).

34
Q

What is pharmacologic classification in drug classification?

A

How the drug produces its effects on the body and its mechanism of action.

35
Q

What is a prototype drug?

A

The drug to which all others in a class are compared.

36
Q

Why are generic names preferred over trade names?

A

Generic names are simpler, consistent, and universally recognized, while trade names can vary, be misleading, or have multiple versions globally.

37
Q

What are the challenges with trade names?

A

A single drug can have multiple trade names, and the same trade name can have different active ingredients in different regions or products.

38
Q

How is a generic name assigned?

A

By the US Adopted Names Council.

39
Q

Why do NCLEX and organizations prefer generic names?

A

To ensure consistency and eliminate confusion—students only need to memorize one name.

40
Q

What is an example of a generic name and its trade names?

A

Generic: Acetaminophen. Trade: Tylenol, Acephen, Aminophen, Apap, Cetafen, Feverall, etc.

41
Q

What is the difference between a generic and trade name?

A

Generic: Assigned by the US Adopted Names Council, consistent across uses. Trade: Given by the pharmaceutical company, proprietary, and can vary.

42
Q

What is the exclusivity period for trade names?

A

A limited time granted to the pharmaceutical company that develops the drug.