misc Flashcards

1
Q

What antibiotic is associated with a high risk of C. difficile-associated diarrhea (CDAD)?

A

Clindamycin

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2
Q

What are the primary uses of clindamycin?

A

Alternative for penicillin (PCN) allergy, severe infections

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3
Q

What is the major caution with clindamycin?

A

Severe C. difficile-associated diarrhea (CDAD)

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4
Q

What antibiotic is used for multidrug-resistant Gram-positive infections, including VRE and MRSA?

A

Linezolid

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5
Q

What are the main adverse effects (AEs) of linezolid?

A

Nausea, vomiting, diarrhea, headache (N/V/D & HA), myelosuppression, neuropathy

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6
Q

What conditions require caution when using linezolid?

A

Phenylketonuria (PKU), MAOIs, SSRIs (risk of serotonin syndrome)

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7
Q

What topical antibiotic is used to treat impetigo?

A

Retapamulin

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8
Q

What is the main adverse effect of retapamulin?

A

Local irritation

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9
Q

What topical antibiotic is used for impetigo and nasal MRSA?

A

Mupirocin

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10
Q

What are the possible adverse effects of mupirocin?

A

Local irritation, headache, rhinitis, congestion, pharyngitis

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