misc Flashcards
What antibiotic is associated with a high risk of C. difficile-associated diarrhea (CDAD)?
Clindamycin
What are the primary uses of clindamycin?
Alternative for penicillin (PCN) allergy, severe infections
What is the major caution with clindamycin?
Severe C. difficile-associated diarrhea (CDAD)
What antibiotic is used for multidrug-resistant Gram-positive infections, including VRE and MRSA?
Linezolid
What are the main adverse effects (AEs) of linezolid?
Nausea, vomiting, diarrhea, headache (N/V/D & HA), myelosuppression, neuropathy
What conditions require caution when using linezolid?
Phenylketonuria (PKU), MAOIs, SSRIs (risk of serotonin syndrome)
What topical antibiotic is used to treat impetigo?
Retapamulin
What is the main adverse effect of retapamulin?
Local irritation
What topical antibiotic is used for impetigo and nasal MRSA?
Mupirocin
What are the possible adverse effects of mupirocin?
Local irritation, headache, rhinitis, congestion, pharyngitis