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STEP1: repro > Pharm: leuprolide > Flashcards

Pharm: leuprolide Flashcards

1
Q

MOA

A

GnRH analog
Agonist when pulsatile
Antagonist when continuous
(downreg GnRH receptor in pit -> low FSH/LH)

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2
Q

Clinical use

A

Pulsatile: infertility

Continous:

  • prostate cancer (+flutamide)
  • uterine fibroids
  • precocious puberty
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3
Q

Toxicity

A

Antiandrogen
Nausea,
Vomiting

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STEP1: repro (41 decks)

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